Frederik Heinrich
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Explore the profile of Frederik Heinrich including associated specialties, affiliations and a list of published articles.
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34
Citations
1418
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Recent Articles
1.
Goetzke C, Massoud M, Frischbutter S, Guerra G, Ferreira-Gomes M, Heinrich F, et al.
Nature
. 2025 Mar;
PMID: 40074901
In a subset of children and adolescents, SARS-CoV-2 infection induces a severe acute hyperinflammatory shock termed multisystem inflammatory syndrome in children (MIS-C) at four to eight weeks after infection. MIS-C...
2.
Wendering D, Amini L, Schlickeiser S, Farrera-Sal M, Schulenberg S, Peter L, et al.
Sci Adv
. 2024 Sep;
10(36):eadn3470.
PMID: 39231218
Regulatory T cells (T cells) hold promise for sustainable therapy of immune disorders. Recent advancements in chimeric antigen receptor development and genome editing aim to enhance the specificity and function...
3.
Biniaris-Georgallis S, Aschman T, Stergioula K, Schreiber F, Jafari V, Taranko A, et al.
Nature
. 2024 Aug;
634(8035):952-960.
PMID: 39137897
In systemic lupus erythematosus, loss of immune tolerance, autoantibody production and immune complex deposition are required but not sufficient for organ damage. How inflammatory signals are initiated and amplified in...
4.
Neumann C, Blume J, Roy U, Teh P, Vasanthakumar A, Beller A, et al.
Nat Immunol
. 2024 May;
25(7):1306.
PMID: 38783161
No abstract available.
5.
Ferreira-Gomes M, Chen Y, Durek P, Rincon-Arevalo H, Heinrich F, Bauer L, et al.
Nat Commun
. 2024 May;
15(1):4182.
PMID: 38755157
Bone marrow plasma cells (BMPC) are the correlate of humoral immunity, consistently releasing antibodies into the bloodstream. It remains unclear if BMPC reflect different activation environments or maturation of their...
6.
Brunner T, Serve S, Marx A, Fadejeva J, Saikali P, Dzamukova M, et al.
Nat Immunol
. 2024 Jan;
25(2):256-267.
PMID: 38172258
The pleiotropic alarmin interleukin-33 (IL-33) drives type 1, type 2 and regulatory T-cell responses via its receptor ST2. Subset-specific differences in ST2 expression intensity and dynamics suggest that transcriptional regulation...
7.
Jani P, Petkau G, Kawano Y, Klemm U, Guerra G, Heinz G, et al.
PLoS Biol
. 2023 Nov;
21(11):e3002015.
PMID: 37983263
Throughout life, hematopoietic stem cells (HSCs), residing in bone marrow (BM), continuously regenerate erythroid/megakaryocytic, myeloid, and lymphoid cell lineages. This steady-state hematopoiesis from HSC and multipotent progenitors (MPPs) in BM...
8.
Shen P, Serve S, Wu P, Liu X, Dai Y, Duran-Hernandez N, et al.
Proc Natl Acad Sci U S A
. 2023 Jul;
120(29):e2207993120.
PMID: 37428931
Osteoarthritis (OA) is a joint disease featuring cartilage breakdown and chronic pain. Although age and joint trauma are prominently associated with OA occurrence, the trigger and signaling pathways propagating their...
9.
Mothes R, Pascual-Reguant A, Koehler R, Liebeskind J, Liebheit A, Bauherr S, et al.
Nat Commun
. 2023 Feb;
14(1):791.
PMID: 36774347
Prolonged lung pathology has been associated with COVID-19, yet the cellular and molecular mechanisms behind this chronic inflammatory disease are poorly understood. In this study, we combine advanced imaging and...
10.
Shen P, Wu P, Maleitzke T, Reisener M, Heinz G, Heinrich F, et al.
Front Bioeng Biotechnol
. 2022 Dec;
10:1046127.
PMID: 36479429
The isolation of chondrocytes from human articular cartilage for single-cell RNA sequencing requires extensive and prolonged tissue digestion at 37 C. Modulations of the transcriptional activity likely take place during...