Frederick J Wilson
Overview
Explore the profile of Frederick J Wilson including associated specialties, affiliations and a list of published articles.
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20
Citations
471
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Recent Articles
11.
Lukey P, Harrison S, Yang S, Man Y, Holman B, Rashidnasab A, et al.
Eur Respir J
. 2019 Feb;
53(3).
PMID: 30765508
Phosphatidylinositol 3-kinases (PI3Ks) and mammalian target of rapamycin (mTOR) play a role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Omipalisib (GSK2126458) is a potent inhibitor of PI3K/mTOR.A randomised, placebo-controlled,...
12.
Coello C, Fisk M, Mohan D, Wilson F, Brown A, Polkey M, et al.
EJNMMI Res
. 2017 May;
7(1):47.
PMID: 28547129
Background: An inflammatory reaction in the airways and lung parenchyma, comprised mainly of neutrophils and alveolar macrophages, is present in some patients with chronic obstructive pulmonary disease (COPD). Thoracic fluorodeoxyglucose...
13.
Chen D, Cheriyan J, Chilvers E, Choudhury G, Coello C, Connell M, et al.
J Nucl Med
. 2017 Jan;
58(2):201-207.
PMID: 28082432
Millions of people are affected by respiratory diseases, leading to a significant health burden globally. Because of the current insufficient knowledge of the underlying mechanisms that lead to the development...
14.
Jobert M, Wilson F
Neuropsychobiology
. 2016 Feb;
72(3-4):165-77.
PMID: 26900936
Pharmaco-electroencephalography (EEG) is a non-invasive method used to assess the effects of pharmacological compounds on the central nervous system by processing the EEG signals which directly reveal the spontaneous synchronised...
15.
Wilson F, Danjou P
Neuropsychobiology
. 2016 Feb;
72(3-4):188-94.
PMID: 26900685
The pharmaceutical industry has been suffering from low clinical success rates of new drugs for some time with particularly high attrition in early clinical development, especially for drugs aimed at...
16.
Duff E, Vennart W, Wise R, Howard M, Harris R, Lee M, et al.
Sci Transl Med
. 2015 Feb;
7(274):274ra16.
PMID: 25673761
The therapeutic effects of centrally acting pharmaceuticals can manifest gradually and unreliably in patients, making the drug discovery process slow and expensive. Biological markers providing early evidence for clinical efficacy...
17.
Wilson F, Leiser S, Ivarsson M, Christensen S, Bastlund J
Drug Discov Today
. 2013 Aug;
19(3):282-8.
PMID: 23954252
Pharmaco-electroencephalography has significant yet unrealised promise as a translatable intermediate biomarker of central pharmacodynamic activity that could help reduce Phase 2 attrition in the development of central nervous system drugs....
18.
Jobert M, Wilson F, Roth T, Ruigt G, Anderer P, Drinkenburg W, et al.
Neuropsychobiology
. 2013 Apr;
67(3):127-67.
PMID: 23548759
The International Pharmaco-EEG Society (IPEG) presents guidelines summarising the requirements for the recording and computerised evaluation of pharmaco-sleep data in man. Over the past years, technical and data-processing methods have...
19.
Rabinovich R, Louvaris Z, Raste Y, Langer D, Van Remoortel H, Giavedoni S, et al.
Eur Respir J
. 2013 Feb;
42(5):1205-15.
PMID: 23397303
Symptoms during physical activity and physical inactivity are hallmarks of chronic obstructive pulmonary disease (COPD). Our aim was to evaluate the validity and usability of six activity monitors in patients...
20.
Jobert M, Wilson F, Ruigt G, Brunovsky M, Prichep L, Drinkenburg W
Neuropsychobiology
. 2012 Oct;
66(4):201-20.
PMID: 23075830
The International Pharmaco-EEG Society (IPEG) presents updated guidelines summarising the requirements for the recording and computerised evaluation of pharmaco-EEG data in man. Since the publication of the first pharmaco-EEG guidelines...