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Frederic Villard

Explore the profile of Frederic Villard including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 325
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Recent Articles
1.
Saad A, Vicini R, Foa N, Villard F, Vez S, Karal-Biechl A, et al.
Klin Monbl Augenheilkd . 2024 Dec; PMID: 39642933
Background: This study aimed to evaluate the current status of ophthalmology residency training in Switzerland and provide insights for enhancing training programs. Materials And Methods: The survey covered demographic data...
2.
Masson A, Villard F, Finger M, DeGottrau P, Gaillard M
Klin Monbl Augenheilkd . 2023 May; 240(4):603-607. PMID: 37164444
No abstract available.
3.
Villard F, DeGottrau P, Gaillard M
Klin Monbl Augenheilkd . 2023 May; 240(4):525-527. PMID: 37164431
No abstract available.
4.
Mesrouze Y, Gubler H, Villard F, Boesch R, Ottl J, Kallen J, et al.
ACS Chem Biol . 2023 Feb; 18(3):643-651. PMID: 36825662
The TEAD transcription factors are the most distal elements of the Hippo pathway, and their transcriptional activity is regulated by several proteins, including YAP. In some cancers, the Hippo pathway...
5.
Bokhovchuk F, Mesrouze Y, Meyerhofer M, Fontana P, Zimmermann C, Villard F, et al.
Protein Sci . 2022 Dec; 32(1):e4545. PMID: 36522189
The yes-associated protein (YAP) regulates the transcriptional activity of the TEAD transcription factors that are key in the control of organ morphogenesis. YAP interacts with TEAD via three secondary structure...
6.
Mesrouze Y, Aguilar G, Bokhovchuk F, Martin T, Delaunay C, Villard F, et al.
Sci Rep . 2020 Oct; 10(1):17442. PMID: 33060790
The most downstream elements of the Hippo pathway, the TEAD transcription factors, are regulated by several cofactors, such as Vg/VGLL1-3. Earlier findings on human VGLL1 and here on human VGLL3...
7.
Velcicky J, Wilcken R, Cotesta S, Janser P, Schlapbach A, Wagner T, et al.
J Med Chem . 2020 Aug; 63(17):9856-9875. PMID: 32856916
G-protein-coupled receptor SUCNR1 (succinate receptor 1 or GPR91) senses the citric cycle intermediate succinate and is implicated in various pathological conditions such as rheumatoid arthritis, liver fibrosis, or obesity. Here,...
8.
Kawanami T, Karki R, Cody E, Liu Q, Liang G, Ksander G, et al.
ACS Med Chem Lett . 2020 Feb; 11(2):188-194. PMID: 32071687
Inhibition of neprilysin (NEP) is widely studied as a therapeutic target for the treatment of hypertension, heart failure, and kidney disease. Sacubitril/valsartan (LCZ696) is a drug approved to reduce the...
9.
Bokhovchuk F, Mesrouze Y, Delaunay C, Martin T, Villard F, Meyerhofer M, et al.
Protein Sci . 2019 Nov; 29(2):509-520. PMID: 31697419
The Hippo pathway is a key signaling pathway in the control of organ size and development. The most distal elements of this pathway, the TEAD transcription factors, are regulated by...
10.
Villard F, Thumann G, Malcles A
JAMA Ophthalmol . 2019 Jul; 137(9):1080-1081. PMID: 31343676
No abstract available.