Frederic Nduhirabandi
Overview
Explore the profile of Frederic Nduhirabandi including associated specialties, affiliations and a list of published articles.
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9
Citations
192
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Recent Articles
1.
Cour M, Pedretti S, Nduhirabandi F, Hacking D, Frias M, Hausenloy D, et al.
Life Sci
. 2024 Oct;
358:123145.
PMID: 39401691
Aim: Activation of both the Survivor Activating Factor Enhancement (SAFE) pathway (including Tumor Necrosis Factor-alpha (TNF-α) and Signal Transducer and Activator of Transcription-3 (STAT-3)) and the sphingolipid signalling pathway (including...
2.
Nduhirabandi F, Maarman G
Molecules
. 2018 Jul;
23(7).
PMID: 30037127
Heart failure is a multifactorial clinical syndrome characterized by the inability of the heart to pump sufficient blood to the body. Despite recent advances in medical management, poor outcomes in...
3.
Jiki Z, Lecour S, Nduhirabandi F
Front Physiol
. 2018 Jun;
9:528.
PMID: 29867569
The role of the diet as well as the impact of the dietary habits on human health and disease is well established. Apart from its sleep regulatory effect, the indoleamine...
4.
Nduhirabandi F, Huisamen B, Strijdom H, Lochner A
Cardiovasc J Afr
. 2017 May;
28(6):362-369.
PMID: 28556852
Aim: Melatonin supplementation reduces insulin resistance and protects the heart in obese rats. However, its role in myocardial glucose uptake remains unknown. This study investigated the effect of short-term melatonin...
5.
Nduhirabandi F, Lamont K, Albertyn Z, Opie L, Lecour S
J Pineal Res
. 2015 Oct;
60(1):39-47.
PMID: 26465095
Melatonin protects the heart against myocardial ischemia/reperfusion injury via the activation of the survivor activating factor enhancement (SAFE) pathway which involves tumor necrosis factor alpha (TNFα) and the signal transducer...
6.
Lamont K, Nduhirabandi F, Adam T, Paul Thomas D, Opie L, Lecour S
Biochem Biophys Res Commun
. 2015 Aug;
465(4):719-24.
PMID: 26296463
We have recently discovered that melatonin, given acutely and directly to the isolated heart at the concentration found in wine, confers cardioprotection against ischemia-reperfusion (I/R). However, whether the presence of...
7.
Nduhirabandi F, Huisamen B, Strijdom H, Blackhurst D, Lochner A
J Pineal Res
. 2014 Sep;
57(3):317-32.
PMID: 25187154
Chronic melatonin treatment has been shown to prevent the harmful effects of diet-induced obesity and reduce myocardial susceptibility to ischaemia-reperfusion injury (IRI). However, the exact mechanism whereby it exerts its...
8.
Lochner A, Huisamen B, Nduhirabandi F
Front Biosci (Elite Ed)
. 2013 Jan;
5(1):305-15.
PMID: 23276991
Melatonin (N-acetyl-5-methoxytryptamine) has been shown by several workers to protect the heart against ischaemia/reperfusion damage. Melatonin, both in the picomolar and micromolar range, significantly reduces infarct size and improves functional...
9.
Nduhirabandi F, Du Toit E, Blackhurst D, Marais D, Lochner A
J Pineal Res
. 2010 Nov;
50(2):171-82.
PMID: 21073520
Obesity, a major risk factor for ischemic heart disease, is associated with increased oxidative stress and reduced antioxidant status. Melatonin, a potent free radical scavenger and antioxidant, has powerful cardioprotective...