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Jerome Larghero

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Articles 186
Citations 4788
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Recent Articles
1.
Boyer O, Bensoussan D, Bonig H, Chabannon C, Clemenceau B, Cuffel A, et al.
Bone Marrow Transplant . 2025 Jan; PMID: 39863732
The accessibility of CAR-T cells in centralized production models faces significant challenges, primarily stemming from logistical complexities and prohibitive costs. However, European Regulation EC No. 1394/2007 introduced a pivotal provision...
2.
Guilbaud L, Roger K, Schmidt A, Chhuon C, Breimann S, Lipecka J, et al.
J Proteomics . 2025 Jan; 313:105372. PMID: 39778765
Despite numerous studies on fetal therapy for myelomeningoceles (MMC), the pathophysiology of this malformation remains poorly understood. This study aimed to analyze the biochemical profile and proteome of amniotic fluid...
3.
Athiel Y, Cariot L, Jouannic J, Maillet C, Mauffre V, Adam C, et al.
Stem Cell Res Ther . 2024 Nov; 15(1):444. PMID: 39568021
Background: The aim of this study was to assess the safety and efficacy of human umbilical cord mesenchymal stromal cells (hUC-MSCs) patch used as an adjuvant therapy in fetal myelomeningocele...
4.
Athiel Y, Jouannic J, Lepine M, Maillet C, de Saint Denis T, Larghero J, et al.
Prenat Diagn . 2024 Oct; 44(12):1530-1535. PMID: 39370541
Myelomeningocele is a birth defect whose clinical manifestations are due both to incomplete neural tube closure and the progressive destruction of exposed neuroepithelium during pregnancy. Two hypotheses have been formulated...
5.
Rabiet L, Jeger-Madiot N, Garcia D, Tosca L, Tachdjian G, Kellouche S, et al.
Sci Rep . 2024 Sep; 14(1):21528. PMID: 39277635
Hepatic spheroids are of high interest in basic research, drug discovery and cell therapy. Existing methods for spheroid culture present advantages and drawbacks. An alternative technology is explored: the hepatic...
6.
Arakelian L, Leger M, Kellouche S, Agniel R, Bruneval P, Allain J, et al.
Adv Biol (Weinh) . 2024 Aug; 8(12):e2400208. PMID: 39162336
The management of extensive tracheal resection followed by circumferential replacement remains a surgical challenge. Numerous techniques are proposed with mixed results. Partial decellularization of the trachea with the removal of...
7.
Candelas A, Vianay B, Gelin M, Faivre L, Larghero J, Blanchoin L, et al.
Development . 2024 Aug; 151(17). PMID: 39136544
Hematopoietic stem and progenitor cells (HSPCs) give rise to all cell types of the hematopoietic system through various processes, including asymmetric divisions. However, the contribution of stromal cells of the...
8.
Thierry B, Arakelian L, Denoyelle F, Larghero J, Wurtz A
Eur J Cardiothorac Surg . 2024 Jul; 66(1). PMID: 38984816
Full Circumferential Tracheal Replacement (FCTR) is a surgical challenge, indicated in rare cases of extensive tracheal resection, with no consensus on surgical technique or materials. A systematic review according to...
9.
Menasche P, Renault N, Hagege A, Puscas T, Bellamy V, Humbert C, et al.
EBioMedicine . 2024 May; 103:105145. PMID: 38713924
Background: There is increased evidence that the effects of stem cells can mostly be duplicated by administration of their secretome which might streamline the translation towards the clinics. Methods: The...
10.
Sitbon A, Hauw-Berlemont C, Mebarki M, Heming N, Mayaux J, Diehl J, et al.
Stem Cell Res Ther . 2024 Apr; 15(1):109. PMID: 38637891
Background: The STROMA-CoV-2 study was a French phase 2b, multicenter, double-blind, randomized, placebo-controlled clinical trial that did not identify a significant efficacy of umbilical cord-derived mesenchymal stromal cells in patients...