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Frederic Ezan

Explore the profile of Frederic Ezan including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 520
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Recent Articles
1.
Chowdhury R, Rose S, Ezan F, Sovadinova I, Babica P, Langouet S
Environ Pollut . 2023 Nov; 342:123047. PMID: 38036087
Microcystin-LR (MC-LR) is a potent hepatotoxin produced by harmful cyanobacterial blooms (CyanoHABs). MC-LR targets highly differentiated hepatocytes expressing organic anion transporting polypeptides OATP1B1 and OATP1B3 that are responsible for hepatocellular...
2.
Cuvellier M, Rose S, Ezan F, Jarry U, De Oliveira H, Bruyere A, et al.
Biofabrication . 2022 Jun; 14(3). PMID: 35696992
In recent decades, 3Dcultures of primary human hepatocytes (PHHs) have been increasingly developed to establish models capable of faithfully mimicking main liver functions. The use of 3D bioprinting, capable of...
3.
Rose S, Cuvellier M, Ezan F, Carteret J, Bruyere A, Legagneux V, et al.
Arch Toxicol . 2021 Nov; 96(1):243-258. PMID: 34762139
The liver is essential in the elimination of environmental and food contaminants. Given the interspecies differences between rodents and humans, the development of relevant in vitro human models is crucial...
4.
Rose S, Ezan F, Cuvellier M, Bruyere A, Legagneux V, Langouet S, et al.
Sci Rep . 2021 Jan; 11(1):515. PMID: 33436872
Generating the proliferation of differentiated normal adult human hepatocytes is a major challenge and an expected central step in understanding the microenvironmental conditions that regulate the phenotype of human hepatocytes...
5.
Cuvellier M, Ezan F, Oliveira H, Rose S, Fricain J, Langouet S, et al.
Biomaterials . 2021 Jan; 269:120611. PMID: 33385685
Bioprinting is an emergent technology that has already demonstrated the capacity to create complex and/or vascularized multicellular structures with defined and organized architectures, in a reproducible and high throughput way....
6.
Rouede D, Schaub E, Bellanger J, Ezan F, Tiaho F
Opt Express . 2020 Mar; 28(4):4845-4858. PMID: 32121716
From P-SHG experiments, second-order nonlinear optical anisotropy parameters ρ = χ/χ of collagen tissues are calculated assuming the same model of supercoiled collagen fibril characterized by a variable angle θ....
7.
Deplanche M, Mouhali N, Nguyen M, Cauty C, Ezan F, Diot A, et al.
Sci Rep . 2019 May; 9(1):7694. PMID: 31118484
Staphylococcus aureus causes serious medical problems in human and animals. Here we show that S. aureus can compromise host genomic integrity as indicated by bacteria-induced histone H2AX phosphorylation, a marker...
8.
Rouede D, Schaub E, Bellanger J, Ezan F, Scimeca J, Baffet G, et al.
Sci Rep . 2017 Sep; 7(1):12197. PMID: 28939903
Polarization dependence second harmonic generation (P-SHG) microscopy is gaining increase popularity for in situ quantification of fibrillar protein architectures. In this report, we combine P-SHG microscopy, new linear least square...
9.
Candido-Bacani P, Ezan F, Figueiredo P, Matos M, Garcez F, Garcez W, et al.
Toxicol Lett . 2017 Mar; 273:44-54. PMID: 28343894
[1-9-NαC]-crourorb A1 is a cyclic peptide isolated from Croton urucurana Baillon latex, found in midwestern Brazil, that has been shown to exert cytotoxic effects against a panel of cancer cell...
10.
Bomo J, Ezan F, Tiaho F, Bellamri M, Langouet S, Theret N, et al.
J Cell Biochem . 2015 Sep; 117(3):708-20. PMID: 26331987
Mechanical forces influence the growth and shape of virtually all tissues and organs. Recent studies show that increased cell contractibility, growth and differentiation might be normalized by modulating cell tensions....