Frederic Emschermann
Overview
Explore the profile of Frederic Emschermann including associated specialties, affiliations and a list of published articles.
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16
Citations
255
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Recent Articles
1.
Guan T, Emschermann F, Schories C, Groga-Bada P, Martus P, Borst O, et al.
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232370
Platelets express the transmembrane chemokine SR-PSOX/CXCL16, proteolytic cleavage of which generates the sCXCL16 soluble-(s) chemokine. The sCXCL16 engages CXCR6 on platelets to synergistically propagate degranulation, aggregation and thrombotic response. Currently,...
2.
Sauter M, Sauter R, Nording H, Olbrich M, Emschermann F, Langer H
STAR Protoc
. 2022 Sep;
3(3):101664.
PMID: 36097382
Different types of immune cells are involved in atherogenesis and may act atheroprotective or atheroprogressive. Here, we describe an in vitro approach to analyze CD11c cells and CD11c-derived ApoE in...
3.
Zdanyte M, Martus P, Nestele J, Bild A, Mizera L, Glatthaar A, et al.
Clin Cardiol
. 2022 Jul;
45(9):943-951.
PMID: 35789499
Background: Cardiovascular risk factors and comorbidities are highly prevalent among COVID-19 patients and are associated with worse outcomes. Hypothesis: We therefore investigated if established cardiovascular risk assessment models could efficiently...
4.
Rath D, Rapp V, Schwartz J, Winter S, Emschermann F, Arnold D, et al.
JACC Basic Transl Sci
. 2022 Jun;
7(5):445-461.
PMID: 35663628
Genetic predisposition through single-nucleotide variation (SNV) influences circulatory soluble junctional adhesion molecule-A (sJAM-A) levels in coronary artery disease (CAD) patients. Homozygous carriers of the minor alleles (SNVs rs2774276, rs790056) show...
5.
Nording H, Sauter M, Lin C, Steubing R, Geisler S, Sun Y, et al.
J Immunol
. 2022 Mar;
208(7):1729-1741.
PMID: 35277420
Recent evidence suggests interaction of platelets with dendritic cells (DCs), while the molecular mechanisms mediating this heterotypic cell cross-talk are largely unknown. We evaluated the role of integrin Mac-1 (αMβ2,...
6.
Nestele J, Rohlfing A, Dicenta V, Bild A, Eissler D, Emschermann F, et al.
Int J Mol Sci
. 2022 Jan;
23(1).
PMID: 35008437
Traditional antithrombotic agents commonly share a therapy-limiting side effect, as they increase the overall systemic bleeding risk. A novel approach for targeted antithrombotic therapy is nanoparticles. In other therapeutic fields,...
7.
Cebo M, Dittrich K, Fu X, Manke M, Emschermann F, Rheinlaender J, et al.
Blood
. 2021 Dec;
139(11):1722-1742.
PMID: 34905596
Platelet ACKR3/CXCR7 surface expression is enhanced and influences prognosis in coronary artery disease (CAD) patients, who exhibit a distinct atherothrombotic platelet lipidome. Current investigation validates the potential of ACKR3/CXCR7 in...
8.
Petersen-Uribe A, Kremser M, Rohlfing A, Castor T, Kolb K, Dicenta V, et al.
Int J Mol Sci
. 2021 Oct;
22(20).
PMID: 34681838
Platelets play a significant role in atherothrombosis. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is critically involved in the regulation of LDL metabolism and interacts with platelet function. The effect of...
9.
Nording H, Baron L, Haberthur D, Emschermann F, Mezger M, Sauter M, et al.
Nat Commun
. 2021 Jun;
12(1):3352.
PMID: 34099640
Platelets contribute to the regulation of tissue neovascularization, although the specific factors underlying this function are unknown. Here, we identified the complement anaphylatoxin C5a-mediated activation of C5a receptor 1 (C5aR1)...
10.
Emschermann F, Zuern C, Patzelt J, Rizas K, Jager G, Eick C, et al.
Int J Cardiol Heart Vasc
. 2017 Jun;
11:80-86.
PMID: 28616530
Background: Factors causing resistance to renal denervation (RDN) for treatment of arterial hypertension are not known. In the current study, we sought to determine mechanisms involved in responsiveness to renal...