Fred Rosche
Overview
Explore the profile of Fred Rosche including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
52
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Recent Articles
1.
Gnoth K, Bar J, Rosche F, Rahfeld J, Demuth H
PLoS One
. 2024 Apr;
19(4):e0289239.
PMID: 38625918
Dipeptidyl peptidase 4 (DP4)/CD26 regulates the biological function of various peptide hormones by releasing dipeptides from their N-terminus. The enzyme is a prominent target for the treatment of type-2 diabetes...
2.
Kirchberg M, Eick S, Buchholz M, Rosche F, Kiesow A, Sarembe S, et al.
Int J Pharm
. 2020 Jul;
586:119578.
PMID: 32615242
We describe the development of flexible minocycline-lipid-complex extrudates with optimized mechanical and drug release properties. These extrudates contain a minocycline - magnesium stearate chelate complex with a higher stability in...
3.
Stephan A, Hahn-Lobmann S, Rosche F, Buchholz M, Giritch A, Gleba Y
Int J Mol Sci
. 2017 Dec;
19(1).
PMID: 29286298
Colicins are natural non-antibiotic bacterial proteins with a narrow spectrum but an extremely high antibacterial activity. These proteins are promising food additives for the control of major pathogenic Shiga toxin-producing...
4.
Wagner L, Wermann M, Rosche F, Rahfeld J, Hoffmann T, Demuth H
Biol Chem
. 2011 Jun;
392(7):665-77.
PMID: 21657982
Abstract In the present studies we resolved the post-translational microheterogeneity of purified porcine dipeptidyl peptidase IV (DP 4) from kidney cortex. Applying SDS-homogeneous DP 4 onto an analytical agarose isoelectric...
5.
Bohme L, Bar J, Hoffmann T, Manhart S, Ludwig H, Rosche F, et al.
Biol Chem
. 2008 Nov;
389(8):1043-53.
PMID: 18979629
Posttranslational modifications influence the structure, stability and biological activity of proteins. Most of the reactions are enzyme-catalyzed, but some, such as asparagine (Asn) and glutamine (Gln) deamidation and the isoaspartate...
6.
Bar J, Rahfeld J, Schulz I, Gans K, Ruiz-Carrillo D, Manhart S, et al.
Adv Exp Med Biol
. 2006 May;
575:103-8.
PMID: 16700513
No abstract available.
7.
Wolf R, Hoffmann T, Rosche F, Demuth H
J Chromatogr B Analyt Technol Biomed Life Sci
. 2004 Mar;
803(1):91-9.
PMID: 15026002
The incretins, glucose-dependent insulinotropic peptide (GIP(1-42)) and glucagon-like peptide 1 (GLP-1(7-36)), are involved in regulation of gastric emptying, glucose homeostasis, body fat regulation and the glucose-induced insulin secretion from the...
8.
Hinke S, Gelling R, Manhart S, Lynn F, Pederson R, Kuhn-Wache K, et al.
Biol Chem
. 2003 Apr;
384(3):403-7.
PMID: 12715891
Six GIP(1-NH2) analogs were synthesized with modifications (de-protonation, N-methylation, reversed chirality, and substitution) at positions 1, 3, and 4 of the N-terminus, and additionally, a cyclized GIP derivative was synthesized....
9.
Hinke S, Lynn F, Ehses J, Pamir N, Manhart S, Kuhn-Wache K, et al.
Adv Exp Med Biol
. 2003 Apr;
524:293-301.
PMID: 12675251
No abstract available.
10.
Baer J, Gerhartz B, Hoffmann T, Rosche F, Demuth H
Adv Exp Med Biol
. 2003 Apr;
524:103-8.
PMID: 12675229
No abstract available.