Fred Bernard
Overview
Explore the profile of Fred Bernard including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
404
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Recent Articles
1.
Lepesant J, Roland-Gosselin F, Guillemet C, Bernard F, Guichet A
Cells
. 2024 Jan;
13(2).
PMID: 38275826
Oogenesis is a developmental process leading to the formation of an oocyte, a haploid gamete, which upon fertilisation and sperm entry allows the male and the female pronuclei to fuse...
2.
Zhu Z, Becam I, Tovey C, Elfarkouchi A, Yen E, Bernard F, et al.
J Cell Biol
. 2023 Sep;
222(10).
PMID: 37698931
Microtubule nucleation is mediated by γ-tubulin ring complexes (γ-TuRCs). In most eukaryotes, a GCP4/5/4/6 "core" complex promotes γ-tubulin small complex (γ-TuSC) association to generate cytosolic γ-TuRCs. Unlike γ-TuSCs, however, this...
3.
Loh M, Bernard F, Guichet A
Development
. 2023 Jun;
150(13).
PMID: 37334771
Microtubules and their associated motors are important players in nucleus positioning. Although nuclear migration in Drosophila oocytes is controlled by microtubules, a precise role for microtubule-associated molecular motors in nuclear...
4.
Bernard F, Jouette J, Durieu C, Le Borgne R, Guichet A, Claret S
Front Cell Dev Biol
. 2021 Sep;
9:719582.
PMID: 34476234
In cell biology, detection of protein subcellular localizations is often achieved by optical microscopy techniques and more rarely by electron microscopy (EM) despite the greater resolution offered by EM. One...
5.
Loh M, Guichet A, Bernard F
J Vis Exp
. 2021 May;
(171).
PMID: 34057446
Live cell imaging is particularly necessary to understand the cellular and molecular mechanisms that regulate organelle movements, cytoskeleton rearrangements, or polarity patterning within the cells. When studying oocyte nucleus positioning,...
6.
Tovey C, Tsuji C, Egerton A, Bernard F, Guichet A, de la Roche M, et al.
J Cell Biol
. 2021 May;
220(8).
PMID: 34042945
γ-Tubulin ring complexes (γ-TuRCs) nucleate microtubules. They are recruited to centrosomes in dividing cells via binding to N-terminal CM1 domains within γ-TuRC-tethering proteins, including Drosophila Centrosomin (Cnn). Binding promotes microtubule...
7.
Mukherjee A, Brooks P, Bernard F, Guichet A, Conduit P
Elife
. 2020 Jul;
9.
PMID: 32657758
Neurons contain polarised microtubule arrays essential for neuronal function. How microtubule nucleation and polarity are regulated within neurons remains unclear. We show that γ-tubulin localises asymmetrically to the somatic Golgi...
8.
Couturier L, Mazouni K, Bernard F, Besson C, Reynaud E, Schweisguth F
Biol Open
. 2017 Nov;
6(12):1851-1860.
PMID: 29101098
In epithelia, mitotic cells round up and push against their neighbors to divide. Mitotic rounding results from increased assembly of F-actin and cortical recruitment of Myosin II, leading to increased...
9.
Bernard F, Lepesant J, Guichet A
Semin Cell Dev Biol
. 2017 Oct;
82:25-33.
PMID: 29056490
Both types of Drosophila egg chamber germ cells, i.e. oocyte and nurse cells, have to control their nucleus positions in order to produce a viable gamete. Interestingly, while actin microfilaments...
10.
Tissot N, Lepesant J, Bernard F, Legent K, Bosveld F, Martin C, et al.
Nat Commun
. 2017 Apr;
8:15168.
PMID: 28447612
Controlling nucleus localization is crucial for a variety of cellular functions. In the Drosophila oocyte, nuclear asymmetric positioning is essential for the reorganization of the microtubule (MT) network that controls...