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Franz Koch

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Articles 11
Citations 322
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Recent Articles
1.
Wein A, Siebler J, Wolff K, Ostermeier N, Busse D, Hagel A, et al.
Anticancer Res . 2017 Jul; 37(7):3771-3779. PMID: 28668873
Background/aim: The aim of this work was to evaluate the efficacy and safety of second-line treatment with weekly high-dose 5-fluorouracil (5-FU) as a 24-hour infusion (24-h inf.) combined with sodium...
2.
Wein A, Siebler J, Goertz R, Wolff K, Ostermeier N, Busse D, et al.
Case Rep Oncol . 2016 Aug; 9(2):379-86. PMID: 27489542
Introduction: The prognostic outcome following progression after palliative first-line treatment for patients suffering from metastatic colorectal adenocarcinoma is generally poor. Long-term relapse-free survival with palliative second-line treatment may be achieved...
3.
Flacher V, Tripp C, Stoitzner P, Haid B, Ebner S, Del Frari B, et al.
J Invest Dermatol . 2009 Nov; 130(3):755-62. PMID: 19890348
Antigen-presenting cells can capture antigens that are deposited in the skin, including vaccines given subcutaneously. These include different dendritic cells (DCs) such as epidermal Langerhans cells (LCs), dermal DCs, and...
4.
Stoecklinger A, Grieshuber I, Scheiblhofer S, Weiss R, Ritter U, Kissenpfennig A, et al.
J Immunol . 2007 Jul; 179(2):886-93. PMID: 17617579
Gene gun immunization, i.e., bombardment of skin with DNA-coated particles, is an efficient method for the administration of DNA vaccines. Direct transfection of APC or cross-presentation of exogenous Ag acquired...
5.
Romani N, Ebner S, Tripp C, Flacher V, Koch F, Stoitzner P
Immunol Lett . 2006 Jul; 106(2):119-25. PMID: 16828878
New experimental models and methods have rendered the field of Langerhans cells very lively. An interesting and productive scientific debate as to the functions of Langerhans cells in vivo is...
6.
Koch F, Ivarsson L, Janke K, Stoitzner P, Ryffel B, Eugster H, et al.
Immunol Lett . 2004 Dec; 96(1):109-20. PMID: 15585314
Dendritic cells are key regulators of immunity and tolerance. TNF-alpha has manifold effects on dendritic cells. It is an indispensable ingredient in several dendritic cell generation protocols, especially in the...
7.
Holzmann S, Tripp C, Schmuth M, Janke K, Koch F, Saeland S, et al.
J Invest Dermatol . 2004 May; 122(5):1165-74. PMID: 15140219
Little is known about the immigration of bone marrow-derived progenitors of Langerhans cells (LC) into the epidermis. We developed an in vivo system based on the tape stripping method that...
8.
Tripp C, Chang-Rodriguez S, Stoitzner P, Holzmann S, Stossel H, Douillard P, et al.
J Invest Dermatol . 2004 Apr; 122(3):670-2. PMID: 15086552
C-type lectin receptors help Langerhans cells (LC) to take up and process pathogens. Langerin/CD207 is a mannose-binding C-type lectin that is specifically expressed by LC. It is involved in antigen...
9.
Romani N, Holzmann S, Tripp C, Koch F, Stoitzner P
APMIS . 2003 Sep; 111(7-8):725-40. PMID: 12974775
Langerhans cells (LC) are dendritic cells of the epidermis. They are highly specialized leukocytes that serve immunogenic and tolerogenic purposes. Here, we review some aspects of LC biology, emphasizing those...
10.
Stoitzner P, Holzmann S, McLellan A, Ivarsson L, Stossel H, Kapp M, et al.
J Invest Dermatol . 2003 Jan; 120(2):266-74. PMID: 12542532
Dendritic cells are professional antigen-presenting cells that initiate primary immunity. Migration from sites of antigen uptake to lymphoid organs is crucial for the generation of immune responses. We investigated the...