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Fransiskus Xaverius Ivan

Explore the profile of Fransiskus Xaverius Ivan including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 201
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Recent Articles
1.
Ivan F, Tiew P, Jaggi T, Thng K, Pang P, Ong T, et al.
Respirology . 2024 Dec; 30(3):217-229. PMID: 39622769
Background And Objective: While the lung microbiome in severe asthma has been studied, work has employed targeted amplicon-based sequencing approaches without functional assessment with none focused on multi-ethnic Asian populations....
2.
Tiew P, Leung J, Mac Aogain M, Johal P, Jaggi T, Yuen A, et al.
Eur Respir J . 2024 Oct; 64(5). PMID: 39362665
Background: Sensitisation to is linked to worse outcomes in patients with COPD; however, its prevalence and clinical implications in domestic (residential) settings remains unknown. Methods: Individuals with COPD (n=43) recruited...
3.
Versi A, Azim A, Ivan F, I Abdel-Aziz M, Bates S, Riley J, et al.
Eur Respir J . 2024 Aug; 64(3). PMID: 39190793
No abstract available.
4.
Versi A, Azim A, Ivan F, I Abdel-Aziz M, Bates S, Riley J, et al.
Clin Transl Med . 2024 Aug; 14(9):e70007. PMID: 39187935
Background: Severe asthma (SA) encompasses several clinical phenotypes with a heterogeneous airway microbiome. We determined the phenotypes associated with a low α-diversity microbiome. Methods: Metagenomic sequencing was performed on sputum...
5.
Meldrum O, Donaldson G, Narayana J, Ivan F, Jaggi T, Mac Aogain M, et al.
Am J Respir Crit Care Med . 2024 Feb; 210(3):298-310. PMID: 38315959
Progressive lung function loss is recognized in chronic obstructive pulmonary disease (COPD); however, no study concurrently evaluates how accelerated lung function decline relates to mucus properties and the microbiome in...
6.
Mac Aogain M, Ivan F, Jaggi T, Richardson H, Shoemark A, Narayana J, et al.
Am J Respir Crit Care Med . 2024 Jan; 210(1):47-62. PMID: 38271608
Chronic infection and inflammation shapes the airway microbiome in bronchiectasis. Utilizing whole-genome shotgun metagenomics to analyze the airway resistome provides insight into interplay between microbes, resistance genes, and clinical outcomes....
7.
Versi A, Ivan F, I Abdel-Aziz M, Bates S, Riley J, Baribaud F, et al.
Allergy . 2023 Jun; 78(11):2906-2920. PMID: 37287344
Background: Because of altered airway microbiome in asthma, we analysed the bacterial species in sputum of patients with severe asthma. Methods: Whole genome sequencing was performed on induced sputum from...
8.
Chan L, Anderson D, Cheng H, Ivan F, Chen S, Kang A, et al.
Nat Commun . 2022 Dec; 13(1):7635. PMID: 36496442
Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation and infective exacerbations, however, in-vitro model systems for the study of host-pathogen interaction at the individual level are lacking. Here,...
9.
Narayana J, Aliberti S, Mac Aogain M, Jaggi T, Ali N, Ivan F, et al.
Am J Respir Crit Care Med . 2022 Oct; 207(7):908-920. PMID: 36288294
Emerging data support the existence of a microbial "gut-lung" axis that remains unexplored in bronchiectasis. Prospective and concurrent sampling of gut (stool) and lung (sputum) was performed in a cohort...
10.
Mac Aogain M, Narayana J, Tiew P, Ali N, Yong V, Jaggi T, et al.
Nat Med . 2021 Apr; 27(4):688-699. PMID: 33820995
Bronchiectasis, a progressive chronic airway disease, is characterized by microbial colonization and infection. We present an approach to the multi-biome that integrates bacterial, viral and fungal communities in bronchiectasis through...