Frans A van der Hoorn
Overview
Explore the profile of Frans A van der Hoorn including associated specialties, affiliations and a list of published articles.
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24
Citations
359
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Recent Articles
1.
Ou Y, Pan C, Zuo J, van der Hoorn F
PLoS One
. 2017 Aug;
12(8):e0183343.
PMID: 28817661
Na,K-ATPase is a membrane protein that catalyzes ATP to maintain transmembrane sodium and potassium gradients. In addition, Na,K-ATPase also acts as a signal-transducing receptor for cardiotonic steroids such as ouabain...
2.
Ou Y, Chan G, Zuo J, Rattner J, van der Hoorn F
J Biol Chem
. 2016 May;
291(29):15388-403.
PMID: 27226580
The tight, relative positioning of the nucleus and centrosome in mammalian cells is important for the regulation of cell migration. Under pathophysiological conditions, the purinergic A2b receptor can regulate cell...
3.
Ou Y, Dores C, Rodriguez-Sosa J, van der Hoorn F, Dobrinski I
Cell Tissue Res
. 2014 Aug;
358(2):597-605.
PMID: 25107611
In vertebrates, a variety of cell types generate a primary cilium. Cilia are implicated in determination and differentiation of a wide variety of organs and during embryonic development. However, there...
4.
Shoji K, Murayama T, Mimura I, Wada T, Kume H, Goto A, et al.
Am J Pathol
. 2013 Apr;
182(6):2191-203.
PMID: 23602831
Hypoxia plays a crucial role in many pathophysiological conditions, including cancer biology, and hypoxia-inducible factor (HIF) regulates transcriptional responses under hypoxia. To elucidate the cellular responses to hypoxia, we performed...
5.
Ou Y, Zhang Y, Cheng M, Rattner J, Dobrinski I, van der Hoorn F
PLoS One
. 2012 Nov;
7(11):e48773.
PMID: 23185275
CRMP-2 plays a pivotal role in promoting axon formation, neurite outgrowth and elongation in neuronal cells. CRMP-2's role in other cells is unknown. Our preliminary results showed CRMP-2 expression in...
6.
Zhang Y, Ou Y, Cheng M, Saadi H, Thundathil J, van der Hoorn F
Dev Biol
. 2012 May;
366(2):101-10.
PMID: 22561200
Kinesin light chain 3 (KLC3) is the only known kinesin light chain expressed in post-meiotic male germ cells. We have reported that in rat spermatids KLC3 associates with outer dense...
7.
Tran M, Aul R, Xu W, van der Hoorn F, Oko R
Biol Reprod
. 2011 Dec;
86(3):84.
PMID: 22156475
This study arose from our finding that SubH2Bv, a histone H2B variant residing in the subacrosomal compartment of mammalian spermatozoa, contains a bipartite nuclear localization signal (bNLS) but in spite...
8.
Ruan Y, Cheng M, Ou Y, Oko R, van der Hoorn F
J Biol Chem
. 2011 Jun;
286(33):29417-29427.
PMID: 21712390
Ornithine decarboxylase antizyme 3 (Oaz3) is expressed in spermatids, makes up the antizyme family of Oaz genes with Oaz1 and Oaz2, and was proposed to encode a 22 kDa antizyme...
9.
Sun Y, Ou Y, Cheng M, Ruan Y, van der Hoorn F
Mol Reprod Dev
. 2011 Jan;
78(2):104-15.
PMID: 21254280
Exposure to nickel has been shown to cause damage to the testis in several animal models. It is not known if the testis expresses protein(s) that can bind nickel. To...
10.
Tarnasky H, Cheng M, Ou Y, Thundathil J, Oko R, van der Hoorn F
BMC Dev Biol
. 2010 Jun;
10:67.
PMID: 20550699
Background: Outer dense fiber protein 2, Odf2, is a major component of the outer dense fibers, ODF, in the flagellum of spermatozoa. ODF are associated with microtubule doublets that form...