Frank Rosl
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Explore the profile of Frank Rosl including associated specialties, affiliations and a list of published articles.
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58
Citations
1060
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Recent Articles
1.
Schafer M, Schneider M, Muller T, Franz N, Braspenning-Wesch I, Stephan S, et al.
J Med Virol
. 2023 Jun;
95(6):e28850.
PMID: 37322807
Infection with certain cutaneous human papillomaviruses (HPV), in conjunction with chronic ultraviolet (UV) exposure, are the major cofactors of non-melanoma skin cancer (NMSC), the most frequent cancer type worldwide. Cutaneous...
2.
Ahmels M, Mariz F, Braspenning-Wesch I, Stephan S, Huber B, Schmidt G, et al.
Front Immunol
. 2022 Oct;
13:1010790.
PMID: 36263027
Licensed L1-VLP-based immunizations against high-risk mucosal human papillomavirus (HPV) types have been a great success in reducing anogenital cancers, although they are limited in their cross-protection against HPV types not...
3.
Hasche D, Ahmels M, Braspenning-Wesch I, Stephan S, Cao R, Schmidt G, et al.
Front Immunol
. 2022 Apr;
13:811094.
PMID: 35359995
Notably, the majority of papillomaviruses associated with a high cancer risk have the potential to translate different isoforms of the L1 major capsid protein. In an infection model, the cutaneous...
4.
Zhuang L, Ly R, Rosl F, Niebler M
Int J Mol Sci
. 2020 Dec;
21(24).
PMID: 33333786
Although the effect of hypoxia on p53 in human papillomavirus (HPV)-positive cancer cells has been studied for decades, the impact of p53 regulation on downstream targets and cellular adaptation processes...
5.
Lambert P, Munger K, Rosl F, Hasche D, Tommasino M
Nature
. 2020 Dec;
588(7838):E20-E21.
PMID: 33328661
No abstract available.
6.
Fu Y, Cao R, Schafer M, Stephan S, Braspenning-Wesch I, Schmitt L, et al.
Elife
. 2020 Aug;
9.
PMID: 32746966
Although many high-risk mucosal and cutaneous human papillomaviruses (HPVs) theoretically have the potential to synthesize L1 isoforms differing in length, previous seroepidemiological studies only focused on the short L1 variants,...
7.
Yang R, Klimentova J, Gockel-Krzikalla E, Ly R, Gmelin N, Hotz-Wagenblatt A, et al.
mSphere
. 2019 Mar;
4(2).
PMID: 30918060
Although the role of high-risk human papillomaviruses (hrHPVs) as etiological agents in cancer development has been intensively studied during the last decades, there is still the necessity of understanding the...
8.
Savini C, Yang R, Savelyeva L, Gockel-Krzikalla E, Hotz-Wagenblatt A, Westermann F, et al.
Int J Mol Sci
. 2019 Mar;
20(5).
PMID: 30836646
Supplementation of micronutrients like folate is a double-edged sword in terms of their ambivalent role in cell metabolism. Although several epidemiological studies support a protective role of folate in carcinogenesis,...
9.
Hasche D, Rosl F
Viruses
. 2019 Feb;
11(2).
PMID: 30795569
Replacements of animal models by advanced in vitro systems in biomedical research, despite exceptions, are currently still not satisfactory in reproducing the whole complexity of pathophysiological mechanisms that finally lead...
10.
Bossler F, Kuhn B, Gunther T, Kraemer S, Khalkar P, Adrian S, et al.
mBio
. 2019 Feb;
10(1).
PMID: 30755508
Hypoxia is linked to therapeutic resistance and poor clinical prognosis for many tumor entities, including human papillomavirus (HPV)-positive cancers. Notably, HPV-positive cancer cells can induce a dormant state under hypoxia,...