Frank Bernardoni
Overview
Explore the profile of Frank Bernardoni including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
42
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Yuan T, Merai D, Gunsch M, Peters R, Lohani S, Bernardoni F, et al.
J Pharm Biomed Anal
. 2024 Jan;
241:115923.
PMID: 38244392
Ion Chromatography (IC) is one of the most widely used methods for analyzing ionic species in pharmaceutical samples. A universal IC method that can separate a wide range of different...
2.
Chen Y, Jo J, Hernandez E, Wang H, Bernardoni F
J Pharm Biomed Anal
. 2023 Jun;
234:115536.
PMID: 37343454
Commercial process of islatravir (MK-8591, EFdA) utilizes biocatalytic cascade reactions to construct the ribose moiety of the molecule which bears three chiral centers. However, this biocatalytic process also brought analytical...
3.
Gunsch M, Schwalm E, Ouimet C, Halsey H, Hamilton S, Bernardoni F, et al.
J Pharm Biomed Anal
. 2022 Feb;
213:114684.
PMID: 35220202
Biocatalytic processes have become more prevalent in the pharmaceutical industry, leading to analytical challenges not faced when characterizing more traditional synthetic routes. A novel one-pot biocatalytic process has been established...
4.
Fier P, Xu Y, Poirier M, Brito G, Zheng M, Bade R, et al.
Org Process Res Dev
. 2022 Jan;
25(12):2806-2815.
PMID: 35095257
Herein is described the development of a large-scale manufacturing process for molnupiravir, an orally dosed antiviral that was recently demonstrated to be efficacious for the treatment of patients with COVID-19....
5.
Bernardoni F, Halsey H, Hartman R, Nowak T, Regalado E
J Pharm Biomed Anal
. 2018 Dec;
165:366-373.
PMID: 30580085
Within the pharmaceutical industry, the determination of residual solvents by Gas Chromatography Flame Ionization Detection (GC-FID) is a highly utilized analytical test that often employs helium (He) as the carrier...
6.
Pirrone G, Mathew R, Makarov A, Bernardoni F, Klapars A, Hartman R, et al.
J Chromatogr B Analyt Technol Biomed Life Sci
. 2018 Feb;
1080:42-49.
PMID: 29477066
Impurity fate and purge studies are critical in order to establish an effective impurity control strategy for approval of the commercial filing application of new medicines. Reversed phase liquid chromatography-diode...
7.
Graffius G, Jocher B, Zewge D, Halsey H, Lee G, Bernardoni F, et al.
J Chromatogr A
. 2017 Sep;
1518:70-77.
PMID: 28882339
Volatile amines are among the most frequently used chemicals in organic and pharmaceutical chemistry. Synthetic route optimization often involves the evaluation of several different amines requiring the development and validation...
8.
Barhate C, Joyce L, Makarov A, Zawatzky K, Bernardoni F, Schafer W, et al.
Chem Commun (Camb)
. 2016 Nov;
53(3):509-512.
PMID: 27872920
Recent developments in fast chromatographic enantioseparations now make high throughput analysis of enantiopurity on the order of a few seconds achievable. Nevertheless, routine chromatographic determinations of enantiopurity to support stereochemical...
9.
Graffius G, Bernardoni F, Fadeev A
Langmuir
. 2014 Nov;
30(49):14797-807.
PMID: 25419641
Methyl-terminated poly(dimethylsiloxanes) (PDMSs) are typically considered to be inert and not suitable for surface functionalization reactions because of the absence of readily hydrolyzable groups. Nevertheless, these siloxanes do react with...
10.
Marques R, Bernardoni F, Pollack S, Helmy R
J Labelled Comp Radiopharm
. 2013 Dec;
57(3):121-4.
PMID: 24327404
Radiolabeled compounds are essential tools in drug development used to obtain critical metabolism and safety information. To support the synthesis and ensure quality of radiolabeled compounds for all programs, bench...