Francois M Abboud
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Explore the profile of Francois M Abboud including associated specialties, affiliations and a list of published articles.
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49
Citations
1684
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Recent Articles
21.
Singh M, Chapleau M, Harwani S, Abboud F
Immunol Res
. 2014 May;
59(1-3):243-53.
PMID: 24847766
A powerful interaction between the autonomic and the immune systems plays a prominent role in the initiation and maintenance of hypertension and significantly contributes to cardiovascular pathology, end-organ damage and...
22.
Santana-Filho V, Davis G, Castania J, Ma X, Salgado H, Abboud F, et al.
Auton Neurosci
. 2014 Feb;
180:24-31.
PMID: 24567955
Activation of the sensory nerve endings of non-myelinated C-fiber afferents evokes release of autocrine/paracrine factors that cause localized vasodilation, neurogenic inflammation, and modulation of sensory nerve activity. The aims of...
23.
Lu Y, Whiteis C, Sluka K, Chapleau M, Abboud F
J Physiol
. 2012 Nov;
591(4):919-32.
PMID: 23165770
Carotid body glomus cells are the primary sites of chemotransduction of hypoxaemia and acidosis in peripheral arterial chemoreceptors. They exhibit pronounced morphological heterogeneity. A quantitative assessment of their functional capacity...
24.
Petroff E, Snitsarev V, Gong H, Abboud F
Biochem Biophys Res Commun
. 2012 Sep;
426(4):511-5.
PMID: 22960074
Acid sensing ion channels (ASICs), Ca(2+) and voltage-activated potassium channels (BK) are widely present throughout the central nervous system. Previous studies have shown that when expressed together in heterologous cells,...
25.
Harwani S, Chapleau M, Legge K, Ballas Z, Abboud F
Circ Res
. 2012 Aug;
111(9):1190-7.
PMID: 22904093
Rationale: Inflammation and autonomic dysfunction contribute to the pathophysiology of hypertension. Cholinergic stimulation suppresses innate immune responses. Angiotensin II (Ang II) induces hypertension and is associated with proinflammatory immune responses....
26.
Abboud F, Harwani S, Chapleau M
Hypertension
. 2012 Feb;
59(4):755-62.
PMID: 22331383
No abstract available.
27.
Abboud F
Am J Physiol Regul Integr Comp Physiol
. 2010 Mar;
298(6):R1449-67.
PMID: 20219871
Walter B. Cannon's research on the sympathetic nervous system and neurochemical transmission was pioneering. Wisdom has endowed our body with a powerful autonomic neural regulation of the circulation that provides...
28.
Sabharwal R, Zhang Z, Lu Y, Abboud F, Russo A, Chapleau M
Hypertension
. 2010 Jan;
55(3):627-35.
PMID: 20100989
Calcitonin gene-related peptide (CGRP) is a powerful vasodilator that interacts with the autonomic nervous system. A subunit of the CGRP receptor complex, receptor activity-modifying protein 1 (RAMP1), is required for...
29.
Lu Y, Ma X, Sabharwal R, Snitsarev V, Morgan D, Rahmouni K, et al.
Neuron
. 2010 Jan;
64(6):885-97.
PMID: 20064394
Arterial baroreceptors provide a neural sensory input that reflexly regulates the autonomic drive of circulation. Our goal was to test the hypothesis that a member of the acid-sensing ion channel...
30.
Tan Z, Lu Y, Whiteis C, Simms A, Paton J, Chapleau M, et al.
Circ Res
. 2009 Dec;
106(3):536-45.
PMID: 20019330
Rationale: Increased sympathetic nerve activity has been linked to the pathogenesis of hypertension in humans and animal models. Enhanced peripheral chemoreceptor sensitivity which increases sympathetic nerve activity has been observed...