Francois M Abboud
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Explore the profile of Francois M Abboud including associated specialties, affiliations and a list of published articles.
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49
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1684
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Recent Articles
11.
Sabharwal R, Mason B, Kuburas A, Abboud F, Russo A, Chapleau M
J Cereb Blood Flow Metab
. 2018 Jan;
39(4):690-703.
PMID: 29297736
Calcitonin gene-related peptide (CGRP) can cause migraines, yet it is also a potent vasodilator that protects against hypertension. Given the emerging role of CGRP-targeted antibodies for migraine prevention, an important...
12.
Abboud F, Singh M
Adv Physiol Educ
. 2017 Nov;
41(4):578-593.
PMID: 29138216
The autonomic nervous system is a powerful regulator of circulatory adjustments to acute hemodynamic stresses. Here we focus on new concepts that emphasize the chronic influence of the sympathetic and...
13.
Wang R, Lu Y, Gunasekar S, Zhang Y, Benson C, Chapleau M, et al.
JCI Insight
. 2017 Mar;
2(5):e90632.
PMID: 28289711
The leucine rich repeat containing protein 8A (LRRC8A), or SWELL1, is an essential component of the volume-regulated anion channel (VRAC) that is activated by cell swelling and ionic strength. We...
14.
Ejection Fraction: Misunderstood and Overrated (Changing the Paradigm in Categorizing Heart Failure)
Konstam M, Abboud F
Circulation
. 2017 Feb;
135(8):717-719.
PMID: 28223323
No abstract available.
15.
Singh M, Cicha M, Kumar S, Meyerholz D, Irani K, Chapleau M, et al.
J Allergy Clin Immunol
. 2017 Jan;
140(3):809-821.e3.
PMID: 28093217
Background: Hypertension is considered an immunologic disorder. However, the role of the IL-17 family in genetic hypertension in the spontaneously hypertensive rat (SHR) has not been investigated. Objective: We tested...
16.
Harwani S, Ratcliff J, Sutterwala F, Ballas Z, Meyerholz D, Chapleau M, et al.
Circ Res
. 2016 Sep;
119(10):1101-1115.
PMID: 27660287
Rationale: Renal inflammation contributes to the pathophysiology of hypertension. CD161a immune cells are dominant in the (SHR) spontaneously hypertensive rat and expand in response to nicotinic cholinergic activation. Objective: We...
17.
Singh M, Cicha M, Meyerholz D, Chapleau M, Abboud F
Hypertension
. 2015 Jul;
66(3):647-56.
PMID: 26195481
Hypertension is recognized as an immune disorder whereby immune cells play a defining role in the genesis and progression of the disease. The innate immune system and its component toll-like...
18.
Abboud F, Benson C
Neuropharmacology
. 2015 Jan;
94:87-98.
PMID: 25592213
In this review we address primarily the role of ASICs in determining sensory signals from arterial baroreceptors, peripheral chemoreceptors, and cardiopulmonary and somatic afferents. Alterations in these sensory signals during...
19.
Chapleau M, Lu Y, Abboud F
Curr Top Membr
. 2014 Aug;
59:541-67.
PMID: 25168149
Baroreceptors (BRs) are mechanosensitive nerve endings in carotid sinuses and aortic arch that function as arterial blood pressure (BP) sensors. Changes in BR activity evoke reflex circulatory adjustments that reduce...
20.
Singh M, Abboud F
Am J Physiol Regul Integr Comp Physiol
. 2014 Jun;
307(5):R501-4.
PMID: 24920728
Hypertension and associated inflammatory processes that accelerate cardiovascular damage are regulated by the innate immune system. Toll-like receptors (TLR) are major components of the innate immune system that recognize endogenous...