Francois-Xavier Theillet
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Explore the profile of Francois-Xavier Theillet including associated specialties, affiliations and a list of published articles.
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39
Citations
1583
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Recent Articles
1.
Shenoy J, Lends A, Berbon M, Bilal M, El Mammeri N, Bertoni M, et al.
Front Mol Biosci
. 2023 Apr;
10:1148302.
PMID: 37065450
Aberrant aggregation of the transactive response DNA-binding protein (TDP-43) is associated with several lethal neurodegenerative diseases, including amyotrophic lateral sclerosis and frontotemporal dementia. Cytoplasmic neuronal inclusions of TDP-43 are enriched...
2.
Theillet F, Luchinat E
Prog Nucl Magn Reson Spectrosc
. 2022 Dec;
132-133:1-112.
PMID: 36496255
NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as early as 1950. We have attempted to gather here in a didactic fashion the broad diversity...
3.
Theillet F
Chem Rev
. 2022 Mar;
122(10):9497-9570.
PMID: 35357148
In-cell structural biology aims at extracting structural information about proteins or nucleic acids in their native, cellular environment. This emerging field holds great promise and is already providing new facts...
4.
Marcelot A, Petitalot A, Ropars V, Le Du M, Samson C, Dubois S, et al.
Nucleic Acids Res
. 2021 Mar;
49(7):3841-3855.
PMID: 33744941
Barrier-to-autointegration factor (BAF), encoded by the BANF1 gene, is an abundant and ubiquitously expressed metazoan protein that has multiple functions during the cell cycle. Through its ability to cross-bridge two...
5.
Verzini S, Shah M, Theillet F, Belsom A, Bieschke J, Wanker E, et al.
J Mol Biol
. 2020 Nov;
432(24):166689.
PMID: 33211011
Heterogeneous aggregates of the human protein α-synuclein (αSyn) are abundantly found in Lewy body inclusions of Parkinson's disease patients. While structural information on classical αSyn amyloid fibrils is available, little...
6.
Bodor A, Haller J, Bouguechtouli C, Theillet F, Nyitray L, Luy B
Anal Chem
. 2020 Aug;
92(18):12423-12428.
PMID: 32786451
Intrinsically disordered proteins (IDPs) constitute an important class of biomolecules with high flexibility. Atomic-resolution studies for these molecules are essentially limited to NMR spectroscopy, which should be performed under physiological...
7.
Julien M, Bouguechtouli C, Alik A, Ghouil R, Zinn-Justin S, Theillet F
Methods Mol Biol
. 2020 Jul;
2141:793-817.
PMID: 32696390
In line with their high accessibility, disordered proteins are exquisite targets of kinases. Eukaryotic organisms use the so-called intrinsically disordered proteins (IDPs) or intrinsically disordered regions of proteins (IDRs) as...
8.
Ehlen A, Martin C, Miron S, Julien M, Theillet F, Ropars V, et al.
Nat Commun
. 2020 Apr;
11(1):1819.
PMID: 32286328
The BRCA2 tumor suppressor protein is involved in the maintenance of genome integrity through its role in homologous recombination. In mitosis, BRCA2 is phosphorylated by Polo-like kinase 1 (PLK1). Here...
9.
Alik A, Bouguechtouli C, Julien M, Bermel W, Ghouil R, Zinn-Justin S, et al.
Angew Chem Int Ed Engl
. 2020 Mar;
59(26):10411-10415.
PMID: 32181947
Abundant phosphorylation events control the activity of nuclear proteins involved in gene regulation and DNA repair. These occur mostly on disordered regions of proteins, which often contain multiple phosphosites. Comprehensive...
10.
Julien M, Miron S, Carreira A, Theillet F, Zinn-Justin S
Biomol NMR Assign
. 2020 Jan;
14(1):79-85.
PMID: 31900740
The Breast Cancer susceptibility protein 2 (BRCA2) is involved in mechanisms that maintain genome stability, including DNA repair, replication and cell division. These functions are ensured by the folded C-terminal...