Franco Di Padova
Overview
Explore the profile of Franco Di Padova including associated specialties, affiliations and a list of published articles.
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21
Citations
1486
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Recent Articles
1.
Kolbinger F, Di Padova F, Deodhar A, Hawkes J, Huppertz C, Kuiper T, et al.
Pharmacol Ther
. 2021 Jun;
229:107925.
PMID: 34171337
Psoriasis, psoriatic arthritis, and axial spondyloarthritis are systemic inflammatory diseases, each commonly manifesting as a spectrum of symptoms, complications, and comorbidities that arise differently in individual patients. Drugs targeting inflammatory...
2.
Di Padova F, Quesniaux V, Ryffel B
Expert Opin Ther Targets
. 2018 Apr;
22(5):401-408.
PMID: 29658361
Myeloid differentiation primary response protein 88 (MyD88) is a critical adaptor protein involved in Toll-like and IL-1 receptor family signaling controlling innate immune responses and inflammation. Genetic deletion of MyD88...
3.
Chenuet P, Fauconnier L, Madouri F, Marchiol T, Rouxel N, Ledru A, et al.
Clin Sci (Lond)
. 2017 Oct;
131(20):2533-2548.
PMID: 29026003
T helper (Th)17 immune response participates in allergic lung inflammation and asthma is reduced in the absence of interleukin (IL)-17 in mice. Since IL-17A and IL-17F are induced and bind...
4.
Li C, Maillet I, Mackowiak C, Viala C, Di Padova F, Li M, et al.
Cell Death Dis
. 2017 Apr;
8(4):e2735.
PMID: 28383552
Atopic dermatitis (AD) is a chronic Th2 type inflammatory skin disorder. Here we report that MyD88 signaling is crucial in the pathogenesis of experimental AD induced by vitamin D3 analog...
5.
Segueni N, Tritto E, Bourigault M, Rose S, Erard F, Le Bert M, et al.
Sci Rep
. 2016 Nov;
6:36923.
PMID: 27853279
Antibodies targeting IL-17A or its receptor IL-17RA show unprecedented efficacy in the treatment of autoimmune diseases such as psoriasis. These therapies, by neutralizing critical mediators of immunity, may increase susceptibility...
6.
Agoro R, Piotet-Morin J, Palomo J, Michaudel C, Vigne S, Maillet I, et al.
Eur J Immunol
. 2016 Aug;
46(11):2531-2541.
PMID: 27569535
Allergic asthma is characterized by a strong Th2 response with inflammatory cell recruitment and structural changes in the lung. Papain is a protease allergen disrupting the airway epithelium triggering a...
7.
Kolbinger F, Huppertz C, Mir A, Di Padova F
Curr Drug Targets
. 2016 Mar;
17(16):1882-1893.
PMID: 26953244
Multiple sclerosis (MS) is an immune mediated demyelinating disease of the central nervous system (CNS). The importance of immune cells to MS pathology is supported by clinical data linking the...
8.
Gomery K, Muller-Loennies S, Brooks C, Brade L, Kosma P, Di Padova F, et al.
Proc Natl Acad Sci U S A
. 2012 Nov;
109(51):20877-82.
PMID: 23184990
Escherichia coli infections, a leading cause of septic shock, remain a major threat to human health because of the fatal action to endotoxin (LPS). Therapeutic attempts to neutralize endotoxin currently...
9.
Nindl V, Maier R, Ratering D, De Giuli R, Zust R, Thiel V, et al.
Eur J Immunol
. 2012 Jun;
42(9):2311-21.
PMID: 22730043
Myocarditis is a potentially lethal inflammatory heart disease of children and young adults that frequently leads to dilated cardiomyopathy (DCM). Since diagnostic procedures and efficient therapies are lacking, it is...
10.
Rampersad R, Tarrant T, Vallanat C, Quintero-Matthews T, Weeks M, Esserman D, et al.
PLoS One
. 2011 Oct;
6(10):e25833.
PMID: 21991368
CCR2 is considered a proinflammatory mediator in many inflammatory diseases such as rheumatoid arthritis. However, mice lacking CCR2 develop exacerbated collagen-induced arthritis. To explore the underlying mechanism, we investigated whether...