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Franco Capozza

Explore the profile of Franco Capozza including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 1183
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Recent Articles
11.
Bonuccelli G, Casimiro M, Sotgia F, Wang C, Liu M, Katiyar S, et al.
Am J Pathol . 2009 Apr; 174(5):1650-62. PMID: 19395651
Here we used the Met-1 cell line in an orthotopic transplantation model in FVB/N mice to dissect the role of the Cav-1(P132L) mutation in human breast cancer. Identical experiments were...
12.
Sotgia F, Casimiro M, Bonuccelli G, Liu M, Whitaker-Menezes D, Er O, et al.
Am J Pathol . 2009 Jan; 174(2):613-29. PMID: 19164602
Here, we show that functional loss of a single gene is sufficient to confer constitutive milk protein production and protection against mammary tumor formation. Caveolin-3 (Cav-3), a muscle-specific caveolin-related gene,...
13.
Chen J, Capozza F, Wu A, DeAngelis T, Sun H, Lisanti M, et al.
J Cell Physiol . 2008 May; 217(1):281-9. PMID: 18506777
The insulin receptor substrate-1 (IRS-1), a docking protein of the type 1 insulin-like growth factor receptor (IGF-IR) plays a significant role in cell proliferation and differentiation. The expression of IRS-1...
14.
Gioiosa L, Raggi C, Ricceri L, Jasmin J, Frank P, Capozza F, et al.
Behav Brain Res . 2007 Dec; 188(2):255-62. PMID: 18083242
Neurological phenotypes associated with loss of caveolin 1 (cav-1) (the defining structural protein in caveolar vesicles, which regulate signal transduction and cholesterol trafficking in cells) in mice have been reported...
15.
Di Vizio D, Sotgia F, Williams T, Hassan G, Capozza F, Frank P, et al.
Cancer Biol Ther . 2007 Sep; 6(8):1263-8. PMID: 17786030
Prostate cancer is the second leading cause of cancer-related deaths in men. Fatty acid synthase (FASN) is normally upregulated during human prostate cancer onset and metastatic progression and its expression...
16.
Bonuccelli G, Sotgia F, Capozza F, Gazzerro E, Minetti C, Lisanti M
Cell Cycle . 2007 May; 6(10):1242-8. PMID: 17495527
Duchenne Muscular Dystrophy (DMD) is an incurable inherited disease of childhood, characterized by progressive muscle degeneration and weakness. Our previous findings supported the idea that dystrophin and associated proteins, absent...
17.
Schubert W, Sotgia F, Cohen A, Capozza F, Bonuccelli G, Bruno C, et al.
Am J Pathol . 2007 Jan; 170(1):316-33. PMID: 17200204
Here, we examine the role of "non-muscle" caveolins (Cav-1 and Cav-2) in skeletal muscle biology. Our results indicate that skeletal muscle fibers from male Cav-1(-/-) and Cav-2(-/-) mice show striking...
18.
Williams T, Sotgia F, Lee H, Hassan G, Di Vizio D, Bonuccelli G, et al.
Am J Pathol . 2006 Oct; 169(5):1784-801. PMID: 17071600
Here, we investigate the role of caveolin-1 (Cav-1) in breast cancer onset and progression, with a focus on epithelial-stromal interactions, ie, the tumor microenvironment. Cav-1 is highly expressed in adipocytes...
19.
Capozza F, Combs T, Cohen A, Cho Y, Park S, Schubert W, et al.
Am J Physiol Cell Physiol . 2005 Feb; 288(6):C1317-31. PMID: 15689413
Caveolin-3 (Cav-3) is expressed predominantly in skeletal muscle fibers, where it drives caveolae formation at the muscle cell's plasma membrane. In vitro studies have suggested that Cav-3 may play a...
20.
Capozza F, Cohen A, Cheung M, Sotgia F, Schubert W, Battista M, et al.
Am J Physiol Cell Physiol . 2004 Nov; 288(3):C677-91. PMID: 15548572
It is generally well accepted that caveolin-3 expression is muscle specific, whereas caveolin-1 and -2 are coexpressed in a variety of cell types, including adipocytes, endothelial cells, epithelial cells, and...