Franck Gesbert
Overview
Explore the profile of Franck Gesbert including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
360
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Recent Articles
1.
Dominguez-Lafage C, Lagana M, Gesbert F, Marin-Esteban V, Schlecht-Louf G, Bachelerie F, et al.
Virologie (Montrouge)
. 2024 Jan;
27(6):333-354.
PMID: 38239028
The virome of the skin, defined as all viruses detected in the skin, represents a significant part of the microbiota. A much more recent discovery than the bacterial flora, the...
2.
Sormani L, Montaudie H, Blot L, Heim M, Cardot Leccia N, Mhaidly R, et al.
J Invest Dermatol
. 2021 Dec;
142(7):1858-1868.e8.
PMID: 34896119
Pigmentation of the human skin is a complex process regulated by many genes. However, only a few have a profound impact on melanogenesis. Transcriptome analysis of pigmented skin compared with...
3.
Colombo S, Petit V, Wagner R, Champeval D, Yajima I, Gesbert F, et al.
Development
. 2021 Dec;
149(2).
PMID: 34878101
The canonical Wnt/β-catenin pathway governs a multitude of developmental processes in various cell lineages, including the melanocyte lineage. Indeed, β-catenin regulates transcription of Mitf-M, the master regulator of this lineage....
4.
Montaudie H, Sormani L, Dadone-Montaudie B, Heim M, Cardot-Leccia N, Tulic M, et al.
J Invest Dermatol
. 2021 Jul;
142(2):425-434.
PMID: 34310951
The potential role of CLEC12B, a gene predominantly expressed by skin melanocytes discovered through transcriptomic analysis, in melanoma is unknown. In this study, we show that CLEC12B expression is lower...
5.
Hamm M, Sohier P, Petit V, Raymond J, Delmas V, Le Coz M, et al.
Nat Commun
. 2021 Jun;
12(1):3707.
PMID: 34140478
While the major drivers of melanoma initiation, including activation of NRAS/BRAF and loss of PTEN or CDKN2A, have been identified, the role of key transcription factors that impose altered transcriptional...
6.
Gesbert F, Larue L
Med Sci (Paris)
. 2018 Jun;
34(5):407-416.
PMID: 29900843
Cutaneous melanoma derives from the tumoral transformation of melanocytes. These pigmented cells produce melanin prior transmitting it to the surrounding keratinocytes of the skin, hair and mane. The main function...
7.
Gudjohnsen S, Atacho D, Gesbert F, Raposo G, Hurbain I, Larue L, et al.
Front Neuroanat
. 2015 Dec;
9:149.
PMID: 26635543
Summary: Melanocytes are pigment producing cells derived from the neural crest. They are primarily found in the skin and hair follicles, but can also be found in other tissues including...
8.
Rambow F, Job B, Petit V, Gesbert F, Delmas V, Seberg H, et al.
Cell Rep
. 2015 Oct;
13(4):840-853.
PMID: 26489459
Molecular signatures specific to particular tumor types are required to design treatments for resistant tumors. However, it remains unclear whether tumors and corresponding cell lines used for drug development share...
9.
Conde-Perez A, Gros G, Longvert C, Pedersen M, Petit V, Aktary Z, et al.
Nat Commun
. 2015 Aug;
6:8093.
PMID: 26307673
Loss of the tumour suppressor PTEN is frequent in human melanoma, results in MAPK activation, suppresses senescence and mediates metastatic behaviour. How PTEN loss mediates these effects is unknown. Here...
10.
Gandji L, Proust R, Larue L, Gesbert F
PLoS One
. 2015 Apr;
10(4):e0123472.
PMID: 25876044
CUB domain-containing protein-1 (CDCP1) is a transmembrane glycoprotein that is phosphorylated by SRC family kinases (SFK) before recruiting and activating PKCδ. CDCP1 is overproduced in many cancers. It promotes metastasis...