Francisco Ruiz-Pino
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Explore the profile of Francisco Ruiz-Pino including associated specialties, affiliations and a list of published articles.
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41
Citations
1189
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Recent Articles
1.
Vazquez M, Daza-Duenas S, Velasco I, Ruiz-Pino F, Sanchez-Tapia M, Manfredi-Lozano M, et al.
Metabolism
. 2024 Dec;
164:156125.
PMID: 39740742
Female reproduction is highly sensitive to body energy stores; persistent energy deficit, as seen in anorexia or strenuous exercise, is known to suppress ovulation via ill-defined mechanisms. We report herein...
2.
Sanchez-Garrido M, Serrano-Lopez V, Ruiz-Pino F, Vazquez M, Rodriguez-Martin A, Torres E, et al.
Nat Commun
. 2024 Oct;
15(1):8498.
PMID: 39353946
Polycystic ovary syndrome (PCOS) is a heterogeneous condition, defined by oligo-/anovulation, hyper-androgenism and/or polycystic ovaries. Metabolic complications are common in patients suffering PCOS, including obesity, insulin resistance and type-2 diabetes,...
3.
Velasco I, Daza-Duenas S, Torres E, Ruiz-Pino F, Vazquez M, Tena-Sempere M
J Neuroendocrinol
. 2024 Jul;
36(10):e13433.
PMID: 39041546
Kisspeptins are essential regulators of the reproductive axis, with capacity to potently activate gonadotropin-releasing hormone neurons, acting also as central conduits for the metabolic regulation of fertility. Recent evidence suggests...
4.
Avendano M, Perdices-Lopez C, Guerrero-Ruiz Y, Ruiz-Pino F, Rodriguez-Sanchez A, Sanchez-Tapia M, et al.
Metabolism
. 2024 May;
157:155932.
PMID: 38729600
Background: Obesity-induced hypogonadism (OIH) is a prevalent, but often neglected condition in men, which aggravates the metabolic complications of overweight. While hypothalamic suppression of Kiss1-encoded kisspeptin has been suggested to...
5.
Velasco I, Franssen D, Daza-Duenas S, Skrapits K, Takacs S, Torres E, et al.
Metabolism
. 2023 Apr;
144:155556.
PMID: 37121307
Background: Kiss1 neurons in the hypothalamic arcuate-nucleus (ARC) play key roles in the control of GnRH pulsatility and fertility. A fraction of ARC Kiss1 neurons, termed KNDy, co-express neurokinin B...
6.
Del Rio C, Ruiz-Pino F, Prados M, Fiebich B, Tena-Sempere M, Munoz E
Front Pharmacol
. 2022 Nov;
13:981817.
PMID: 36339540
Cannabidiol (CBD) has been suggested as a potential therapy for inflammatory and fibrotic diseases. Cannabidiol was demonstrated to reduce alcohol-induced liver inflammation and steatosis but its specific activity on the...
7.
Roa J, Ruiz-Cruz M, Ruiz-Pino F, Onieva R, Vazquez M, Sanchez-Tapia M, et al.
Nat Commun
. 2022 Aug;
13(1):4663.
PMID: 35945211
Kiss1 neurons, producing kisspeptins, are essential for puberty and fertility, but their molecular regulatory mechanisms remain unfolded. Here, we report that congenital ablation of the microRNA-synthesizing enzyme, Dicer, in Kiss1...
8.
Romero-Pico A, Novelle M, Al-Massadi O, Beiroa D, Tojo M, Heras V, et al.
Int J Mol Sci
. 2022 Mar;
23(6).
PMID: 35328539
Weight gain is a hallmark of decreased estradiol (E2) levels because of menopause or following surgical ovariectomy (OVX) at younger ages. Of note, this weight gain tends to be around...
9.
Perdices-Lopez C, Avendano M, Barroso A, Gaytan F, Ruiz-Pino F, Vazquez M, et al.
Metabolism
. 2022 Jan;
129:155141.
PMID: 35074314
Background: Perturbations in the timing of puberty, with potential adverse consequences in later health, are increasingly common. The underlying neurohormonal mechanisms are unfolded, but nutritional alterations are key contributors. Efforts...
10.
Burgaz S, Garcia C, Gonzalo-Consuegra C, Gomez-Almeria M, Ruiz-Pino F, Unciti J, et al.
Molecules
. 2021 Dec;
26(24).
PMID: 34946726
Cannabinoids act as pleiotropic compounds exerting, among others, a broad-spectrum of neuroprotective effects. These effects have been investigated in the last years in different preclinical models of neurodegeneration, with the...