Francisco Llavero
Overview
Explore the profile of Francisco Llavero including associated specialties, affiliations and a list of published articles.
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19
Citations
246
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Recent Articles
1.
Llavero F, Zugaza J
Biochem Soc Trans
. 2024 Apr;
52(3):1265-1274.
PMID: 38661212
The three isoforms of glycogen phosphorylase - PYGM, PYGB, and PYGL - are expressed in glial cells. Unlike PYGB and PYGL, PYGM is the only isoform regulated by Rac1. This...
2.
Arrazola Sastre A, Luque Montoro M, Llavero F, Zugaza J
Cells
. 2023 Jul;
12(14).
PMID: 37508540
Protein O-GlcNAcylation has been associated with neurodegenerative diseases such as Alzheimer's disease (AD). The O-GlcNAcylation of the Amyloid Precursor Protein (APP) regulates both the trafficking and the processing of the...
3.
Ortiz-Sanz C, Llavero F, Zuazo-Ibarra J, Balantzategi U, Quintela-Lopez T, Wyssenbach A, et al.
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628557
Glial cells participate actively in the early cognitive decline in Alzheimer's disease (AD) pathology. In fact, recent studies have found molecular and functional abnormalities in astrocytes and microglia in both...
4.
Llavero F, Alejo L, Fiuza-Luces C, Lopez Soto A, Valenzuela P, Castillo-Garcia A, et al.
Exerc Immunol Rev
. 2021 May;
27:125-141.
PMID: 33965896
Background: Regular exercise, particularly moderate-intensity continuous training (MICT), can improve immune function. Natural killer (NK) cells, a subset of lymphocytes that react to infections, are the most responsive innate immune...
5.
Arrazola Sastre A, Luque Montoro M, Lacerda H, Llavero F, Zugaza J
Int J Mol Sci
. 2021 Apr;
22(9).
PMID: 33922618
Small guanosine triphosphatases (GTPases) of the Rab and Arf families are key regulators of vesicle formation and membrane trafficking. Membrane transport plays an important role in the central nervous system....
6.
Arrazola Sastre A, Luque Montoro M, Galvez-Martin P, Lacerda H, Lucia A, Llavero F, et al.
Int J Mol Sci
. 2020 Sep;
21(17).
PMID: 32878220
Small guanosine triphosphatases (GTPases) of the Ras superfamily are key regulators of many key cellular events such as proliferation, differentiation, cell cycle regulation, migration, or apoptosis. To control these biological...
7.
Hampel H, Vergallo A, Caraci F, Cuello A, Lemercier P, Vellas B, et al.
Neuropharmacology
. 2020 May;
185:108081.
PMID: 32407924
When Alzheimer's disease (AD) disease-modifying therapies will be available, global healthcare systems will be challenged by a large-scale demand for clinical and biological screening. Validation and qualification of globally accessible,...
8.
Santos-Lozano A, Valenzuela P, Llavero F, Lista S, Carrera-Bastos P, Hampel H, et al.
Aging (Albany NY)
. 2020 Feb;
12(4):3502-3515.
PMID: 32100723
Healthy aging depends on a complex gene-environment network that is ultimately reflected in the expression of different proteins. We aimed to perform a comparative analysis of the plasma proteome of...
9.
Llavero F, Arrazola Sastre A, Luque Montoro M, Galvez P, Lacerda H, Parada L, et al.
Int J Mol Sci
. 2019 Nov;
20(23).
PMID: 31775340
McArdle disease, also known as glycogen storage disease type V (GSDV), is characterized by exercise intolerance, the second wind phenomenon, and high serum creatine kinase activity. Here, we recapitulate mutations...
10.
Llavero F, Arrazola Sastre A, Luque Montoro M, Martin M, Arenas J, Lucia A, et al.
Small GTPases
. 2019 Sep;
12(2):106-113.
PMID: 31512989
Small GTPases, together with their regulatory and effector molecules, are key intermediaries in the complex signalling pathways that control almost all cellular processes, working as molecular switches to transduce extracellular...