Francisco J Alonso
Overview
Explore the profile of Francisco J Alonso including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
1390
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Recent Articles
1.
De Los Santos-Jimenez J, Campos-Sandoval J, Rosales T, Ko B, Alonso F, Marquez J, et al.
Int J Mol Sci
. 2025 Jan;
26(1.
PMID: 39796278
Glutaminase controls the first step in glutaminolysis, impacting bioenergetics, biosynthesis and oxidative stress. Two isoenzymes exist in humans, GLS and GLS2. GLS is considered prooncogenic and overexpressed in many tumours,...
2.
De Los Santos-Jimenez J, Campos-Sandoval J, Alonso F, Marquez J, Mates J
Antioxidants (Basel)
. 2024 Jun;
13(6).
PMID: 38929183
A pathway frequently altered in cancer is glutaminolysis, whereby glutaminase (GA) catalyzes the main step as follows: the deamidation of glutamine to form glutamate and ammonium. There are two types...
3.
De Los Santos-Jimenez J, Rosales T, Ko B, Campos-Sandoval J, Alonso F, Marquez J, et al.
Cancers (Basel)
. 2023 Jan;
15(2).
PMID: 36672480
Most tumor cells can use glutamine (Gln) for energy generation and biosynthetic purposes. Glutaminases (GAs) convert Gln into glutamate and ammonium. In humans, GAs are encoded by two genes: and...
4.
Campos-Sandoval J, Gomez-Garcia M, De Los Santos-Jimenez J, Mates J, Alonso F, Marquez J
Neurochem Int
. 2021 Jul;
149:105136.
PMID: 34274381
Glioblastoma remains one of the most challenging and devastating cancers, with only a very small proportion of patients achieving 5-year survival. The current standard of care consists of surgery, followed...
5.
De Los Santos-Jimenez J, Campos-Sandoval J, Marquez-Torres C, Urbano-Polo N, Brondegaard D, Martin-Rufian M, et al.
J Biomed Sci
. 2021 Feb;
28(1):14.
PMID: 33610185
Background: Glutaminase isoenzymes GLS and GLS2 play apparently opposing roles in cancer: GLS acts as an oncoprotein, while GLS2 (GAB isoform) has context specific tumour suppressive activity. Some microRNAs (miRNAs)...
6.
Lopez de la Oliva A, Campos-Sandoval J, Gomez-Garcia M, Cardona C, Martin-Rufian M, Sialana F, et al.
Sci Rep
. 2021 Jan;
11(1):249.
PMID: 33397990
No abstract available.
7.
Lopez de la Oliva A, Campos-Sandoval J, Gomez-Garcia M, Cardona C, Martin-Rufian M, Sialana F, et al.
Sci Rep
. 2020 Feb;
10(1):2259.
PMID: 32042057
Glutaminase (GA) catalyzes the first step in mitochondrial glutaminolysis playing a key role in cancer metabolic reprogramming. Humans express two types of GA isoforms: GLS and GLS2. GLS isozymes have...
8.
Romero-Sanchez F, Bermejo-Garcia J, Barrios-Muriel J, Alonso F
Front Neurorobot
. 2019 Aug;
13:58.
PMID: 31417390
Hybrid orthoses or rehabilitation exoskeletons have proven to be a powerful tool for subjects with gait disabilities due to their combined use of electromechanical actuation to provide motion and support,...
9.
Mates J, Campos-Sandoval J, De Los Santos-Jimenez J, Segura J, Alonso F, Marquez J
Curr Med Chem
. 2019 May;
27(32):5317-5339.
PMID: 31038055
Background: Metabolic reprogramming of tumours is a hallmark of cancer. Among the changes in the metabolic network of cancer cells, glutaminolysis is a key reaction altered in neoplasms. Glutaminase proteins...
10.
Garcia-Bonilla M, Garcia-Martin M, Munoz-Hernandez M, Dominguez-Pinos D, Martinez-Leon M, Penalver A, et al.
J Neuropathol Exp Neurol
. 2018 Oct;
77(12):1122-1136.
PMID: 30364991
In congenital hydrocephalus, cerebrospinal fluid accumulation is associated with increased intracranial pressure (ICP), ischemia/hypoxia, metabolic impairment, neuronal damage, and astrocytic reaction. The aim of this study was to identify whether...