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Francisco E Lopez-Salas

Explore the profile of Francisco E Lopez-Salas including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 44
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Recent Articles
1.
Mascotte-Cruz J, Vera A, Leija L, Lopez-Salas F, Gradzielski M, Koetz J, et al.
Discov Nano . 2024 Apr; 19(1):60. PMID: 38564106
Neurotensin-polyplex nanoparticles provide efficient gene transfection of nigral dopaminergic neurons when intracerebrally injected in preclinical trials of Parkinson's disease because they do not cross the blood-brain barrier (BBB). Therefore, this...
2.
Valdez-Cruz N, Rosiles-Becerril D, Martinez-Olivares C, Garcia-Hernandez E, Cobos-Marin L, Garzon D, et al.
Microb Cell Fact . 2024 Feb; 23(1):41. PMID: 38321489
Background: Developing effective vaccines against SARS-CoV-2 that consider manufacturing limitations, equitable access, and acceptance is necessary for developing platforms to produce antigens that can be efficiently presented for generating neutralizing...
3.
Gatica-Garcia B, Bannon M, Martinez-Davila I, Soto-Rojas L, Reyes-Corona D, Escobedo L, et al.
Neural Regen Res . 2024 Jan; 19(9):2057-2067. PMID: 38227536
JOURNAL/nrgr/04.03/01300535-202409000-00039/figure1/v/2024-01-16T170235Z/r/image-tiff Parkinsonism by unilateral, intranigral β-sitosterol β-D-glucoside administration in rats is distinguished in that the α-synuclein insult begins unilaterally but spreads bilaterally and increases in severity over time, thus replicating...
4.
Luna-Herrera C, Martinez-Davila I, Soto-Rojas L, Flores-Martinez Y, Fernandez-Parrilla M, Ayala-Davila J, et al.
J Immunol Res . 2020 Dec; 2020:5907591. PMID: 33282962
Chronic consumption of -sitosterol--D-glucoside (BSSG), a neurotoxin contained in cycad seeds, leads to Parkinson's disease in humans and rodents. Here, we explored whether a single intranigral administration of BSSG triggers...
5.
Lopez-Salas F, Nadella R, Maldonado-Berny M, Escobedo-Sanchez M, Fiorentino-Perez R, Gatica-Garcia B, et al.
Mol Pharm . 2020 Oct; 17(12):4572-4588. PMID: 33125243
Neurotensin (NTS)-polyplex is a multicomponent nonviral vector that enables gene delivery via internalization of the neurotensin type 1 receptor (NTSR1) to dopaminergic neurons and cancer cells. An approach to improving...
6.
Soto-Rojas L, Martinez-Davila I, Luna-Herrera C, Gutierrez-Castillo M, Lopez-Salas F, Gatica-Garcia B, et al.
Acta Neuropathol Commun . 2020 Apr; 8(1):56. PMID: 32321590
The spreading and accumulation of α-synuclein and dopaminergic neurodegeneration, two hallmarks of Parkinson's disease (PD), have been faithfully reproduced in rodent brains by chronic, oral administration of β-sitosterol β-D-glucoside (BSSG)....
7.
Soto-Rojas L, Banuelos C, Garces-Ramirez L, Luna-Herrera C, Flores-Martinez Y, Soto-Rodriguez G, et al.
MethodsX . 2020 Mar; 7:100821. PMID: 32195138
An animal model, suitable for resembling Parkinson's disease (PD) progress, should show both, motor and non-motor alterations. However, these features have been scarcely evaluated or developed in parkinsonian models induced...
8.
Soto-Rojas L, Garces-Ramirez L, Luna-Herrera C, Flores-Martinez Y, Soto-Rodriguez G, Gatica-Garcia B, et al.
Behav Brain Res . 2019 Oct; 378:112279. PMID: 31606429
Parkinson's disease (PD) is a progressive neuropathology characterized by motor and non-motor alterations. β-sitosterol β-d-glucoside (BSSG) is a neurotoxin whose prolonged oral administration in rats has been proposed as a...