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Francis Yew Fu Tieng

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Citations 125
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Recent Articles
1.
Tieng F, Abdullah-Zawawi M, Md Shahri N, Mohamed-Hussein Z, Lee L, Mutalib N
Brief Bioinform . 2023 Dec; 25(1). PMID: 38040490
RNA biology has risen to prominence after a remarkable discovery of diverse functions of noncoding RNA (ncRNA). Most untranslated transcripts often exert their regulatory functions into RNA-RNA complexes via base...
2.
Mohd Yunos R, Mutalib N, Khoo J, Saidin S, Ishak M, Syafruddin S, et al.
Front Mol Biosci . 2023 Mar; 9:997747. PMID: 36866106
The incidences of colorectal cancer (CRC) are continuously increasing in some areas of the world, including Malaysia. In this study, we aimed to characterize the landscape of somatic mutations using...
3.
Tieng F, Lee L, Mutalib N
Front Immunol . 2022 Aug; 13:959705. PMID: 36032085
Single cell RNA sequencing (scRNA-seq) is a novel high-throughput technique that enables the investigation of a single cell's entire transcriptome. It elucidates intricate cellular networks and generates indices that will...
4.
Tieng F, Abu N, Nasir S, Lee L, Mutalib N
Diagnostics (Basel) . 2021 Nov; 11(11). PMID: 34829483
Colorectal cancer (CRC) is ranked second for cancer-related deaths worldwide with approximately half of the patients being diagnosed at the late stages. The untimely detection of CRC results in advancement...
5.
Tieng F, Abu N, Lee L, Mutalib N
Diagnostics (Basel) . 2021 Apr; 11(3). PMID: 33803882
Colorectal cancer (CRC) is the third most commonly-diagnosed cancer in the world and ranked second for cancer-related mortality in humans. Microsatellite instability (MSI) is an indicator for Lynch syndrome (LS),...
6.
Tieng F, Abu N, Sukor S, Mohd Azman Z, Mahamad Nadzir N, Lee L, et al.
Diagnostics (Basel) . 2020 Jul; 10(7). PMID: 32630086
Background: Colorectal cancer (CRC) screening at the earlier stages could effectively decrease CRC-related mortality and incidence; however, accurate screening strategies are still lacking. Considerable interest has been generated in the...
7.
Mohd Yunos R, Ab Mutalib N, Tieng F, Abu N, Jamal R
Biomolecules . 2020 Apr; 10(3). PMID: 32245111
Global statistics have placed colorectal cancer (CRC) as the third most frequently diagnosed cancer and the fourth principal cause of cancer-related deaths worldwide. Improving survival for CRC is as important...
8.
Tieng F, Baharudin R, Abu N, Mohd Yunos R, Lee L, Mutalib N
Front Pharmacol . 2020 Mar; 11:135. PMID: 32174835
Colorectal cancer (CRC) is among the most common cancer worldwide, a challenge for research, and a model for studying the molecular mechanisms involved in its development. Previously, bulk transcriptomics analyses...
9.
Baharudin R, Tieng F, Lee L, Ab Mutalib N
Cancers (Basel) . 2020 Feb; 12(2). PMID: 32074995
Secreted frizzled-related protein 1 (SFRP1) is a gene that belongs to the secreted glycoprotein SFRP family. has been classified as a tumor suppressor gene due to the loss of expression...
10.
Tieng F, Latifah S, Md Hashim N, Khazaai H, Ahmat N, Gopalsamy B, et al.
Molecules . 2019 Jul; 24(14). PMID: 31323836
Breast cancer is the most common and the second leading cause of cancer-related deaths in women. It has two distinctive hallmarks: rapid abnormal growth and the ability to invade and...