Francis X McGowan Jr
Overview
Explore the profile of Francis X McGowan Jr including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
713
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0
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Recent Articles
1.
Weiss S, Henrickson S, Lindell R, Sartori L, Zhang D, Bush J, et al.
Shock
. 2021 Dec;
57(5):630-638.
PMID: 34966070
Introduction: Peripheral blood mononuclear cells (PBMCs) are commonly used to compare mitochondrial function in patients with versus without sepsis, but how these measurements in this mixed cell population vary by...
2.
Weiss S, Bittinger K, Lee J, Friedman E, Mattei L, Graham K, et al.
Crit Care Explor
. 2021 Mar;
3(3):e0360.
PMID: 33786436
Objectives: The intestinal microbiome can modulate immune function through production of microbial-derived short-chain fatty acids. We explored whether intestinal dysbiosis in children with sepsis leads to changes in microbial-derived short-chain...
3.
Garcia-Marcinkiewicz A, Kovatsis P, Hunyady A, Olomu P, Zhang B, Sathyamoorthy M, et al.
Lancet
. 2020 Dec;
396(10266):1905-1913.
PMID: 33308472
Background: Orotracheal intubation of infants using direct laryngoscopy can be challenging. We aimed to investigate whether video laryngoscopy with a standard blade done by anaesthesia clinicians improves the first-attempt success...
4.
Weiss S, Zhang D, Bush J, Graham K, Starr J, Murray J, et al.
Shock
. 2019 Nov;
54(3):285-293.
PMID: 31764621
Objective: Immune dysregulation is a defining feature of sepsis, but the role for mitochondria in the development of immunoparalysis in pediatric sepsis is not known. We sought to determine if...
5.
Weiss S, Zhang D, Bush J, Graham K, Starr J, Tuluc F, et al.
Crit Care Med
. 2019 Aug;
47(10):1433-1441.
PMID: 31385882
Objectives: Limited data exist about the timing and significance of mitochondrial alterations in children with sepsis. We therefore sought to determine if alterations in mitochondrial respiration and content within circulating...
6.
Olbrecht V, Skowno J, Marchesini V, Ding L, Jiang Y, Ward C, et al.
Anesthesiology
. 2017 Oct;
128(1):85-96.
PMID: 29019815
Background: General anesthesia during infancy is associated with neurocognitive abnormalities. Potential mechanisms include anesthetic neurotoxicity, surgical disease, and cerebral hypoxia-ischemia. This study aimed to determine the incidence of low cerebral...
7.
Kussman B, Laussen P, Benni P, McGowan Jr F, McElhinney D
Anesth Analg
. 2017 May;
125(1):234-240.
PMID: 28514318
Background: Increased hemoglobin (Hb) concentration accompanying hypoxemia is a compensatory response to maintain tissue oxygen delivery. Near infrared spectroscopy (NIRS) is used clinically to detect abnormalities in the balance of...
8.
Fiadjoe J, Nishisaki A, Jagannathan N, Hunyady A, Greenberg R, Reynolds P, et al.
Lancet Respir Med
. 2015 Dec;
4(1):37-48.
PMID: 26705976
Background: Despite the established vulnerability of children during airway management, remarkably little is known about complications in children with difficult tracheal intubation. To address this concern, we developed a multicentre...
9.
Wesley M, Pereira L, Scharp L, Emani S, McGowan Jr F, DiNardo J
Anesthesiology
. 2015 Jan;
122(4):746-58.
PMID: 25585004
Background: Tranexamic acid (TXA) is one of the most commonly used antifibrinolytic medications in children undergoing repair of congenital heart defects. However, a pharmacokinetics analysis of TXA has never been...
10.
Costello J, Dunbar-Masterson C, Allan C, Gauvreau K, Newburger J, McGowan Jr F, et al.
Circ Heart Fail
. 2014 Jun;
7(4):596-604.
PMID: 24906491
Background: We sought to determine whether empirical nesiritide or milrinone would improve the early postoperative course after Fontan surgery. We hypothesized that compared with milrinone or placebo, patients assigned to...