Francis X Farrell
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Explore the profile of Francis X Farrell including associated specialties, affiliations and a list of published articles.
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13
Citations
413
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Recent Articles
1.
Wilkinson P, Farrell F, Morel D, Law W, Murphy S
Ann Clin Lab Sci
. 2016 Jul;
46(4):339-45.
PMID: 27466291
Interstitial renal fibrosis is a major pathophysiological manifestation of patients diagnosed with Chronic Kidney Disease (CKD), Diabetic Nephropathy (DN) and other inflammatory diseases. Adenosine signaling is an innate autocrine and...
2.
Perlman A, Chevalier J, Wilkinson P, Liu H, Parker T, Levine D, et al.
Ann Clin Lab Sci
. 2015 Jun;
45(3):256-63.
PMID: 26116588
Background: Diabetes is the leading cause of end stage renal disease (ESRD) in the United States, representing 44% of incident cases [1]. In this study, serum and peripheral blood collected...
3.
Awad A, You H, Gao T, Cooper T, Nedospasov S, Vacher J, et al.
Kidney Int
. 2015 Jun;
88(4):722-33.
PMID: 26061548
Monocyte/macrophage recruitment correlates strongly with the progression of diabetic nephropathy. Tumor necrosis factor-α (TNF-α) is produced by monocytes/macrophages but the direct role of TNF-α and/or macrophage-derived TNF-α in the progression...
4.
Dudas P, Sague S, Elloso M, Farrell F
Nephron Exp Nephrol
. 2010 Oct;
117(4):e114-23.
PMID: 20924205
Background/aims: Interleukin-17A (IL-17A) is a T cell-derived inflammatory cytokine that is upregulated during renal allograft rejection. The present study sought to further describe the IL-17A-mediated proinflammatory/profibrotic activity of proximal tubule...
5.
Glass W, Argentieri R, Bracht M, Farrell F, Das A, Del Vecchio A, et al.
Cytokine
. 2009 Feb;
46(1):17-23.
PMID: 19232499
Given that CD4+ cells are found in the lungs of patients with fibrotic lung diseases such as idiopathic pulmonary fibrosis (IPF) we hypothesized that IL-16, a potent chemoattractant for CD4+...
6.
Murray L, Hackett T, Warner S, Shaheen F, Argentieri R, Dudas P, et al.
PLoS One
. 2008 Dec;
3(12):e4039.
PMID: 19112509
Bone morphogenic protein (BMP)-7 is a member of the BMP family which are structurally and functionally related, and part of the TGFbeta super family of growth factors. BMP-7 has been...
7.
Dudas P, Argentieri R, Farrell F
Nephrol Dial Transplant
. 2008 Dec;
24(5):1406-16.
PMID: 19056781
Background: In rodent models of chronic renal disease bone morphogenetic protein-7 (BMP-7) has been shown to halt disease progression and promote recovery. Subsequent studies utilizing immortalized rodent renal cell lines...
8.
Murray L, Argentieri R, Farrell F, Bracht M, Sheng H, Whitaker B, et al.
Int J Biochem Cell Biol
. 2008 Apr;
40(10):2174-82.
PMID: 18395486
One of the hallmarks of idiopathic pulmonary fibrosis with a usual interstitial pneumonia histological pathology (IPF/UIP) is excess collagen deposition, due to enhanced fibroblast extracellular matrix synthetic activity. Studies using...
9.
Swencki-Underwood B, Mills J, Vennarini J, Boakye K, Luo J, Pomerantz S, et al.
Protein Expr Purif
. 2007 Nov;
57(2):312-9.
PMID: 17977014
Bone morphogenetic protein-7 (BMP-7, OP-1) is a secreted growth factor that is predominantly known for its osteoinductive properties, though it has also been implicated as having a role in mammalian...
10.
LaMontagne K, Butler J, Marshall D, Tullai J, Gechtman Z, Hall C, et al.
Mol Cancer Ther
. 2006 Mar;
5(2):347-55.
PMID: 16505108
We investigated the significance of erythropoietin receptor (EPOR) expression following treatment with recombinant human erythropoietin (rHuEPO; epoetin alpha) and the effect of recombinant epoetins (epoetin alpha, epoetin beta, and darbepoetin...