Francesco Ramirez
Overview
Explore the profile of Francesco Ramirez including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
89
Citations
4627
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Cantalupo A, Asano K, Dikalov S, Gordon D, Ramirez F
J Vasc Res
. 2025 Jan;
:1-13.
PMID: 39827863
Introduction: The pathogenic role of nitric oxide (NO) signaling during development of thoracic aortic aneurysm (TAA) in Marfan syndrome (MFS) is currently unclear. We characterized vasomotor function and its relationship...
2.
Sun Y, Asano K, Sedes L, Cantalupo A, Hansen J, Iyengar R, et al.
JCI Insight
. 2023 Apr;
8(10).
PMID: 37022786
To improve our limited understanding of the pathogenesis of thoracic aortic aneurysm (TAA) that leads to acute aortic dissection, single-cell RNA sequencing (scRNA-seq) was employed to profile disease-relevant transcriptomic changes...
3.
Sedes L, Wondimu E, Crockett B, Hansen J, Cantalupo A, Asano K, et al.
Hum Mol Genet
. 2022 May;
31(19):3281-3289.
PMID: 35567544
A disproportionate tall stature is the most evident manifestation in Marfan syndrome (MFS), a multisystem condition caused by mutations in the extracellular protein and TGFβ modulator, fibrillin-1. Unlike cardiovascular manifestations,...
4.
Asano K, Cantalupo A, Sedes L, Ramirez F
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163812
Fibrillin-1 is the major structural component of the 10 nm-diameter microfibrils that confer key physical and mechanical properties to virtually every tissue, alone and together with elastin in the elastic...
5.
Asano K, Cantalupo A, Sedes L, Ramirez F
Biomolecules
. 2022 Jan;
12(1).
PMID: 35053276
About 20% of individuals afflicted with thoracic aortic disease have single-gene mutations that predispose the vessel to aneurysm formation and/or acute aortic dissection often without associated syndromic features. One widely...
6.
Caescu C, Hansen J, Crockett B, Xiao W, Arnaud P, Spronck B, et al.
Arterioscler Thromb Vasc Biol
. 2021 Jul;
41(9):2483-2493.
PMID: 34320838
Objective: Despite considerable research, the goal of finding nonsurgical remedies against thoracic aortic aneurysm and acute aortic dissection remains elusive. We sought to identify a novel aortic PK (protein kinase)...
7.
Rifkin D, Sachan N, Singh K, Sauber E, Tellides G, Ramirez F
Dev Dyn
. 2021 Mar;
251(1):95-104.
PMID: 33742701
The purpose of this review is to discuss the transforming growth factor beta (TGFB) binding proteins (LTBP) with respect to their participation in the activity of TGFB. We first describe...
8.
Tran P, Skrba T, Wondimu E, Galatioto G, Svensson R, Olesen A, et al.
Physiol Rep
. 2019 Nov;
7(21):e14267.
PMID: 31724332
Fibrillin-1 mutations cause pathological changes in connective tissue that constitute the complex phenotype of Marfan syndrome. In this study, we used fibrillin-1 hypomorphic and haploinsufficient mice (Fbn1 and Fbn1 mice,...
9.
Hansen J, Galatioto J, Caescu C, Arnaud P, Calizo R, Spronck B, et al.
JCI Insight
. 2019 Jun;
4(11).
PMID: 31167969
Marfan syndrome (MFS) is associated with mutations in fibrillin-1 that predispose afflicted individuals to progressive thoracic aortic aneurysm (TAA) leading to dissection and rupture of the vessel wall. Here we...
10.
Milewicz D, Ramirez F
Arterioscler Thromb Vasc Biol
. 2019 Jan;
39(2):126-136.
PMID: 30651002
Thoracic aortic aneurysms that progress to acute aortic dissections are often fatal. Thoracic aneurysms have been managed with treatment with β-adrenergic blocking agents (β-blockers) and routine surveillance imaging, followed by...