Francesca Zonta
Overview
Explore the profile of Francesca Zonta including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
185
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0
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Recent Articles
1.
Zonta F, Borgo C, Quezada Meza C, Masgras I, Rasola A, Salvi M, et al.
Cells
. 2021 Jan;
10(1).
PMID: 33477590
CK2 is a Ser/Thr protein kinase overexpressed in many cancers. It is usually present in cells as a tetrameric enzyme, composed of two catalytic (α or α') and two regulatory...
2.
Dalle Vedove A, Zonta F, Zanforlin E, Demitri N, Ribaudo G, Cazzanelli G, et al.
Eur J Med Chem
. 2020 Apr;
195:112267.
PMID: 32283296
Protein kinase CK2 sustains cancer growth, especially in hematological malignancies. Its inhibitor SRPIN803, based on a 6-methylene-5-imino-1,3,4-thiadiazolopyrimidin-7-one scaffold, showed notable specificity. Our synthesis of the initially proposed SRPIN803 resulted in...
3.
Cozza G, Zonta F, Dalle Vedove A, Venerando A, DallAcqua S, Battistutta R, et al.
FEBS J
. 2019 Oct;
287(9):1850-1864.
PMID: 31661600
Protein kinase CK2 is an antiapoptotic cancer-sustaining protein. Curcumin, reported previously as a CK2 inhibitor, is too bulky to be accommodated in the CK2 active site and rapidly degrades in...
4.
Di Paolo M, Cozza G, Milelli A, Zonta F, Sarno S, Minniti E, et al.
FEBS J
. 2019 Jul;
286(24):4995-5015.
PMID: 31291696
The two human monoamine oxidase isoforms (namely MAO A and MAO B) are enzymes involved in the catabolism of monoamines, including neurotransmitters, and for this reason are well-known and attractive...
5.
Zampini M, Tregnago C, Bisio V, Simula L, Borella G, Manara E, et al.
Leukemia
. 2018 Feb;
32(5):1124-1134.
PMID: 29472719
The somatic translocation t(8;21)(q22;q22)/RUNX1-RUNX1T1 is one of the most frequent rearrangements found in children with standard-risk acute myeloid leukemia (AML). Despite the favorable prognostic role of this aberration, we recently...
6.
Tibaldi E, Pagano M, Frezzato F, Trimarco V, Facco M, Zagotto G, et al.
Haematologica
. 2017 Jun;
102(8):1401-1412.
PMID: 28619847
Lyn, a member of the Src family of kinases, is a key factor in the dysregulation of survival and apoptotic pathways of malignant B cells in chronic lymphocytic leukemia. One...
7.
Lupo F, Tibaldi E, Matte A, Sharma A, Brunati A, Alper S, et al.
Blood
. 2016 Oct;
128(25):2976-2987.
PMID: 27742708
Chorea-acanthocytosis is one of the hereditary neurodegenerative disorders known as the neuroacanthocytoses. Chorea-acanthocytosis is characterized by circulating acanthocytes deficient in chorein, a protein of unknown function. We report here for...
8.
Zonta F, Pagano M, Trentin L, Tibaldi E, Frezzato F, Trimarco V, et al.
Blood
. 2015 May;
125(24):3747-55.
PMID: 25931585
Aberrant protein kinase activities, and the consequent dramatic increase of Ser/Thr and -Tyr phosphorylation, promote the deregulation of the survival pathways in chronic lymphocytic leukemia (CLL), which is crucial to...
9.
Grancara S, Zonta F, Ohkubo S, Brunati A, Agostinelli E, Toninello A
Amino Acids
. 2015 Mar;
47(5):869-83.
PMID: 25792113
Mitochondria, once merely considered as the "powerhouse" of cells, as they generate more than 90 % of cellular ATP, are now known to play a central role in many metabolic...
10.
Frezzato F, Trimarco V, Martini V, Gattazzo C, Ave E, Visentin A, et al.
Br J Haematol
. 2014 Mar;
165(5):659-72.
PMID: 24606526
Functional abnormalities of chronic lymphocytic leukaemia (CLL) cells may be related to the microtubular network of cell cytoskeleton; specifically tubulin involvement in cells after B-cell receptor engagement. As microtubule inhibitors...