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Francesca Pennati

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Recent Articles
1.
Vincenzi E, Buccardi M, Ferrini E, Fantazzini A, Polverini E, Villetti G, et al.
J Transl Med . 2024 Nov; 22(1):1040. PMID: 39558387
Background: Drug discovery strongly relies on the thorough evaluation of preclinical experimental studies. In the context of pulmonary fibrosis, micro-computed tomography (µCT) and histology are well-established and complementary tools for...
2.
Buseghin D, Grandi A, Ferrini E, Villetti G, Ciccimarra R, Sverzellati N, et al.
Respir Res . 2024 Oct; 25(1):393. PMID: 39478545
Background: Idiopathic Pulmonary Fibrosis (IPF), prevalently affecting individuals over 60 years of age, has been mainly studied in young mouse models. The limited efficacy of current treatments underscores the need...
3.
Molani A, Pennati F, Ravazzani S, Scarpellini A, Storti F, Vegetali G, et al.
Sensors (Basel) . 2024 Oct; 24(20). PMID: 39460161
The need for faster and more accessible alternatives to laboratory microscopy is driving many innovations throughout the image and data acquisition chain in the biomedical field. Benchtop microscopes are bulky,...
4.
Pennati F, Aliboni L, Aliverti A
Diagnostics (Basel) . 2024 Sep; 14(17). PMID: 39272764
Geometrical models of the airways offer a comprehensive perspective on the complex interplay between lung structure and function. Originating from mathematical frameworks, these models have evolved to include detailed lung...
5.
Buccardi M, Grandi A, Ferrini E, Buseghin D, Villetti G, Civelli M, et al.
Sci Rep . 2024 Jun; 14(1):14792. PMID: 38926490
Idiopathic Pulmonary Fibrosis (IPF) is a debilitating and fatal lung disease characterized by the excessive formation of scar tissue and decline of lung function. Despite extensive research, only two FDA-approved...
6.
Gonsard A, Mekov E, Barron S, Castellana G, Khurtsidze E, Vontetsianos A, et al.
ERJ Open Res . 2024 May; 10(3). PMID: 38770003
It is a challenge to keep abreast of all the clinical and scientific advances in the field of respiratory medicine. This article contains an overview of laboratory-based science, clinical trials...
7.
Grandi A, Ferrini E, Zoboli M, Buseghin D, Pennati F, Khalajzeyqami Z, et al.
Am J Physiol Lung Cell Mol Physiol . 2024 Apr; 326(6):L736-L753. PMID: 38651940
Systemic sclerosis (SSc) with interstitial lung disease (SSc-ILD) lacks curative pharmacological treatments, thus necessitating effective animal models for candidate drug discovery. Existing bleomycin (BLM)-induced SSc-ILD mouse models feature spatially limited...
8.
Pennati F, Belenkov S, Buccardi M, Ferrini E, Sverzellati N, Villetti G, et al.
iScience . 2024 Mar; 27(3):109262. PMID: 38433926
Micro-computed tomography derived functional biomarkers used in lung disease research can significantly complement end-stage histomorphometric measures while also allowing for longitudinal studies. However, no approach for visualizing lung dynamics across...
9.
Santini A, Protti A, Pennati F, Dalla Corte F, Martinetti N, Pugliese L, et al.
Acta Anaesthesiol Scand . 2024 Mar; 68(5):626-634. PMID: 38425207
Background: High positive end-expiratory pressure (PEEP>10 cmHO) is commonly used in mechanically ventilated hypoxemic patients with COVID-19. However, some epidemiological and physiological studies indirectly suggest that using a lower PEEP...
10.
Cambianica A, Marchese V, Pennati F, Faustinelli A, Migliorati M, Roda F, et al.
Int J Environ Res Public Health . 2024 Jan; 21(1). PMID: 38248566
Penitentiaries have a higher burden of communicable diseases compared to the general population. Prisoners should be tested for hepatitis C virus (HCV) and have direct access to treatment. We analysed...