Frances E Pearson
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Explore the profile of Frances E Pearson including associated specialties, affiliations and a list of published articles.
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13
Citations
305
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Recent Articles
1.
To Tweet or Not to Tweet: A Longitudinal Analysis of Social Media Use by Global Diabetes Researchers
Leigh S, Noble M, Pearson F, Iremonger J, Williams D
Pharmaceut Med
. 2021 Dec;
35(6):353-365.
PMID: 34874534
Background: Engaging influential stakeholders in meaningful exchange is essential for pharmaceutical companies aiming to improve care. At a time where opportunities for face-to-face engagement are limited, the ability to interact, ...
2.
Lee Y, OBrien L, Walpole C, Pearson F, Leal-Rojas I, Masterman K, et al.
J Immunother Cancer
. 2021 Mar;
9(3).
PMID: 33737342
Background: The conventional type 1 dendritic cell subset (cDC1) is indispensable for tumor immune responses and the efficacy of immune checkpoint inhibitor (ICI) therapies in animal models but little is...
3.
Masterman K, Haigh O, Tullett K, Leal-Rojas I, Walpole C, Pearson F, et al.
J Immunother Cancer
. 2020 Aug;
8(2).
PMID: 32737142
Background: Dendritic cells (DCs) are crucial for the efficacy of cancer vaccines, but current vaccines do not harness the key cDC1 subtype required for effective CD8 T-cell-mediated tumor immune responses....
4.
Pearson F, Tullett K, Leal-Rojas I, Haigh O, Masterman K, Walpole C, et al.
Clin Transl Immunology
. 2020 Jun;
9(6):e1141.
PMID: 32547743
Objectives: Vaccines that prime Wilms' tumor 1 (WT1)-specific CD8 T cells are attractive cancer immunotherapies. However, immunogenicity and clinical response rates may be enhanced by delivering WT1 to CD141 dendritic...
5.
Pearson F, Chang K, Minoda Y, Leal Rojas I, Haigh O, Daraj G, et al.
Immunol Cell Biol
. 2018 Jan;
96(4):390-400.
PMID: 29344995
Mice reconstituted with human hematopoietic stem cells are valuable models to study aspects of the human immune system in vivo. We describe a humanized mouse model (hu mice) in which...
6.
Leal Rojas I, Mok W, Pearson F, Minoda Y, Kenna T, Barnard R, et al.
Front Immunol
. 2017 Sep;
8:971.
PMID: 28878767
Dendritic cells (DC) initiate the differentiation of CD4 helper T cells into effector cells including Th1 and Th17 responses that play an important role in inflammation and autoimmune disease pathogenesis....
7.
Muller D, Pearson F, Fernando G, Agyei-Yeboah C, Owens N, Corrie S, et al.
Sci Rep
. 2016 Feb;
6:22094.
PMID: 26911254
Polio eradication is progressing rapidly, and the live attenuated Sabin strains in the oral poliovirus vaccine (OPV) are being removed sequentially, starting with type 2 in April 2016. For risk...
8.
Pearson F, Muller D, Roalfe L, Zancolli M, Goldblatt D, Kendall M
Vaccine
. 2015 Nov;
33(48):6675-83.
PMID: 26518398
Adequate access to effective and affordable vaccines is essential for the prevention of mortality due to infectious disease. Pneumonia--a consequence of Streptococcus pneumoniae infection--is the world's leading cause of death...
9.
Pearson F, OMahony C, Moore A, Hill A
Vaccine
. 2015 Apr;
33(28):3248-55.
PMID: 25839104
There is an urgent need for improvements in vaccine delivery technologies. This is particularly pertinent for vaccination programmes within regions of limited resources, such as those required for adequate provision...
10.
Depelsenaire A, Meliga S, McNeilly C, Pearson F, Coffey J, Haigh O, et al.
J Invest Dermatol
. 2014 Apr;
134(9):2361-2370.
PMID: 24714201
Vaccines delivered to the skin by microneedles-with and without adjuvants-have increased immunogenicity with lower doses than standard vaccine delivery techniques such as intramuscular or intradermal injection. However, the mechanisms underlying...