Kirsteen M Tullett
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Explore the profile of Kirsteen M Tullett including associated specialties, affiliations and a list of published articles.
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17
Citations
523
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Recent Articles
1.
Chua Y, Draper S, Le S, de Menezes M, Ganley M, Ge Z, et al.
Cell Rep
. 2025 Feb;
44(2):115295.
PMID: 39946236
We recently demonstrated that vaccines comprising antigenic peptides conjugated to a glycolipid agonist, termed glycolipid-peptide (GLP) vaccines, efficiently generate substantial numbers of long-lived CD8 liver-resident memory T (Trm) cells that...
2.
Venkatraman R, Balka K, Wong W, Sivamani J, Magill Z, Tullett K, et al.
iScience
. 2024 Sep;
27(9):110693.
PMID: 39262777
The cGAS-STING pathway responds to cytosolic DNA to elicit host immunity to infection. The activation of stimulator of interferon genes (STING) can trigger a number of critical cellular responses including...
3.
Song R, Bafit M, Tullett K, Tan P, Lahoud M, OKeeffe M, et al.
Methods Protoc
. 2024 Mar;
7(2).
PMID: 38525778
The generation of bone-marrow-derived dendritic cells is a widely used approach in immunological research to study antigen processing and presentation, as well as T-cell activation responses. However, the initial step...
4.
Li J, Panetta F, OKeeffe M, Leal Rojas I, Radford K, Zhang J, et al.
J Immunol
. 2021 Sep;
207(7):1836-1847.
PMID: 34479944
DEC-205 is a cell-surface receptor that transports bound ligands into the endocytic pathway for degradation or release within lysosomal endosomes. This receptor has been reported to bind a number of...
5.
Tullett K, Tan P, Park H, Schittenhelm R, Michael N, Li R, et al.
Elife
. 2020 Dec;
9.
PMID: 33264090
The dendritic cell receptor Clec9A facilitates processing of dead cell-derived antigens for cross-presentation and the induction of effective CD8 T cell immune responses. Here, we show that this process is...
6.
Kato Y, Steiner T, Park H, Hitchcock R, Zaid A, Hor J, et al.
J Immunol
. 2020 Aug;
205(7):1842-1856.
PMID: 32839238
Follicular dendritic cells and macrophages have been strongly implicated in presentation of native Ag to B cells. This property has also occasionally been attributed to conventional dendritic cells (cDC) but...
7.
Masterman K, Haigh O, Tullett K, Leal-Rojas I, Walpole C, Pearson F, et al.
J Immunother Cancer
. 2020 Aug;
8(2).
PMID: 32737142
Background: Dendritic cells (DCs) are crucial for the efficacy of cancer vaccines, but current vaccines do not harness the key cDC1 subtype required for effective CD8 T-cell-mediated tumor immune responses....
8.
Holz L, Chua Y, de Menezes M, Anderson R, Draper S, Compton B, et al.
Sci Immunol
. 2020 Jun;
5(48).
PMID: 32591409
Liver resident-memory CD8 T cells (T cells) can kill liver-stage -infected cells and prevent malaria, but simple vaccines for generating this important immune population are lacking. Here, we report the...
9.
Pearson F, Tullett K, Leal-Rojas I, Haigh O, Masterman K, Walpole C, et al.
Clin Transl Immunology
. 2020 Jun;
9(6):e1141.
PMID: 32547743
Objectives: Vaccines that prime Wilms' tumor 1 (WT1)-specific CD8 T cells are attractive cancer immunotherapies. However, immunogenicity and clinical response rates may be enhanced by delivering WT1 to CD141 dendritic...
10.
Valencia-Hernandez A, Ng W, Ghazanfari N, Ghilas S, de Menezes M, Holz L, et al.
Cell Host Microbe
. 2020 May;
27(6):950-962.e7.
PMID: 32396839
Liver-resident memory CD8 T (T) cells remain in and constantly patrol the liver to elicit rapid immunity upon antigen encounter and can mediate efficient protection against liver-stage Plasmodium infection. This...