Franca Salamino
Overview
Explore the profile of Franca Salamino including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
22
Citations
222
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Averna M, Bavestrello M, Cresta F, Pedrazzi M, De Tullio R, Minicucci L, et al.
Arch Biochem Biophys
. 2016 Jun;
604:103-12.
PMID: 27349634
Matrix metalloproteinase 9 (MMP9) is physiologically involved in remodeling the extracellular matrix components but its abnormal release has been observed in several human pathologies. We here report that peripheral blood...
2.
Averna M, Pellegrini M, Cervetto C, Pedrazzi M, Bavestrello M, De Tullio R, et al.
PLoS One
. 2015 Oct;
10(10):e0139750.
PMID: 26431040
We have recently demonstrated that in resting conditions calpain 1, but not calpain 2, is specifically associated to the N-Methyl-D-Aspartate receptor (NMDAR) multiprotein complex. We are here reporting that in...
3.
Averna M, De Tullio R, Pedrazzi M, Bavestrello M, Pellegrini M, Salamino F, et al.
PLoS One
. 2015 Jan;
10(1):e0116738.
PMID: 25575026
Here we demonstrate that heat shock protein 90 (HSP90) interacts with calpain-1, but not with calpain-2, and forms a discrete complex in which the protease maintains its catalytic activity, although...
4.
De Tullio R, Averna M, Pedrazzi M, Sparatore B, Salamino F, Pontremoli S, et al.
Biochim Biophys Acta
. 2014 Jul;
1843(11):2583-91.
PMID: 25026177
Here we demonstrate that the presence of the L-domain in calpastatins induces biphasic interaction with calpain. Competition experiments revealed that the L-domain is involved in positioning the first inhibitory unit...
5.
Averna M, Pedrazzi M, Minicucci L, De Tullio R, Cresta F, Salamino F, et al.
PLoS One
. 2013 Jun;
8(6):e66089.
PMID: 23785472
A basal calpain activity promotes the limited proteolysis of wild type (WT) cystic fibrosis conductance regulator (CFTR), inducing the internalization of the split channel. This process contributes to the regulation...
6.
Pedrazzi M, Averna M, Sparatore B, Patrone M, Salamino F, Marcoli M, et al.
PLoS One
. 2012 Sep;
7(8):e44518.
PMID: 22952988
Background: Extracellular high mobility group box 1 (HMGB1) protein can operate in a synergistic fashion with different signal molecules promoting an increase of cell Ca(2+) influx. However, the mechanisms responsible...
7.
Averna M, Stifanese R, De Tullio R, Minicucci L, Cresta F, Palena S, et al.
Biochim Biophys Acta
. 2011 Oct;
1812(12):1649-57.
PMID: 21983488
We are here reporting that in peripheral blood mononuclear cells (PBMC) of patients homozygous for F508del-CFTR the calpain-calpastatin system undergoes a profound alteration. In fact, calpain basal activity, almost undetectable...
8.
Averna M, Stifanese R, Grosso R, Pedrazzi M, De Tullio R, Salamino F, et al.
Biochim Biophys Acta
. 2010 Nov;
1813(1):50-9.
PMID: 21111762
We are here showing that peripheral mononuclear blood cells (PBMC) from cystic fibrosis (CF) patients contain almost undetectable amounts of mature 170 kDa CF-transmembrane conductance regulator (CFTR) and a highly...
9.
Averna M, Stifanese R, Grosso R, Pedrazzi M, De Tullio R, Salamino F, et al.
Biochem J
. 2010 Jun;
430(2):255-63.
PMID: 20557290
The level of the mature native 170 kDa form of CFTR (cystic fibrosis transmembrane conductance regulator) at the plasma membrane is under the control of a selective proteolysis catalysed by...
10.
Stifanese R, Averna M, De Tullio R, Pedrazzi M, Beccaria F, Salamino F, et al.
J Biol Chem
. 2009 Nov;
285(1):631-43.
PMID: 19880516
Persistent dysregulation in Ca(2+) homeostasis is a pervasive pathogenic mechanism in most neurodegenerative diseases, and accordingly, calpain activation has been implicated in neuronal cells dysfunction and death. In this study...