Franca Golin-Bisello
Overview
Explore the profile of Franca Golin-Bisello including associated specialties, affiliations and a list of published articles.
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13
Citations
662
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Recent Articles
1.
Woodcock C, Huang Y, Woodcock S, Salvatore S, Singh B, Golin-Bisello F, et al.
J Biol Chem
. 2017 Nov;
293(4):1120-1137.
PMID: 29158255
Triple-negative breast cancer (TNBC) comprises ∼20% of all breast cancers and is the most aggressive mammary cancer subtype. Devoid of the estrogen and progesterone receptors, along with the receptor tyrosine...
2.
Wendell S, Golin-Bisello F, Wenzel S, Sobol R, Holguin F, Freeman B
J Biol Chem
. 2015 Jan;
290(9):5868-80.
PMID: 25586183
15-Hydroxyprostaglandin dehydrogenase (15PGDH) is the primary enzyme catalyzing the conversion of hydroxylated arachidonic acid species to their corresponding oxidized metabolites. The oxidation of hydroxylated fatty acids, such as the conversion...
3.
Snyder N, Golin-Bisello F, Gao Y, Blair I, Freeman B, Wendell S
Chem Biol Interact
. 2014 Dec;
234:144-53.
PMID: 25450232
Bioactive lipids govern cellular homeostasis and pathogenic inflammatory processes. Current dogma holds that bioactive lipids, such as prostaglandins and lipoxins, are inactivated by 15-hydroxyprostaglandin dehydrogenase (15PGDH). In contrast, the present...
4.
Khoo N, Mo L, Zharikov S, Kamga-Pride C, Quesnelle K, Golin-Bisello F, et al.
Free Radic Biol Med
. 2014 Feb;
70:45-53.
PMID: 24556414
Though it is well accepted that adipose tissue is central in the regulation of glycemic homeostasis, the molecular mechanisms governing adipocyte glucose uptake remain unclear. Recent studies demonstrate that mitochondrial...
5.
Kelley E, Baust J, Bonacci G, Golin-Bisello F, Devlin J, St Croix C, et al.
Cardiovasc Res
. 2014 Jan;
101(3):352-63.
PMID: 24385344
Aims: Obesity is a risk factor for diabetes and cardiovascular diseases, with the incidence of these disorders becoming epidemic. Pathogenic responses to obesity have been ascribed to adipose tissue (AT)...
6.
Bonacci G, Baker P, Salvatore S, Shores D, Khoo N, Koenitzer J, et al.
J Biol Chem
. 2012 Nov;
287(53):44071-82.
PMID: 23144452
The oxidation and nitration of unsaturated fatty acids by oxides of nitrogen yield electrophilic derivatives that can modulate protein function via post-translational protein modifications. The biological mechanisms accounting for fatty...
7.
Schopfer F, Cole M, Groeger A, Chen C, Khoo N, Woodcock S, et al.
J Biol Chem
. 2010 Jan;
285(16):12321-33.
PMID: 20097754
The peroxisome proliferator-activated receptor-gamma (PPARgamma) binds diverse ligands to transcriptionally regulate metabolism and inflammation. Activators of PPARgamma include lipids and anti-hyperglycemic drugs such as thiazolidinediones (TZDs). Recently, TZDs have raised...
8.
Khoo N, Rudolph V, Cole M, Golin-Bisello F, Schopfer F, Woodcock S, et al.
Free Radic Biol Med
. 2009 Oct;
48(2):230-9.
PMID: 19857569
Reactive oxygen species mediate a decrease in nitric oxide (NO) bioavailability and endothelial dysfunction, with secondary oxidized and nitrated by-products of these reactions contributing to the pathogenesis of numerous vascular...
9.
Cole M, Rudolph T, Khoo N, Motanya U, Golin-Bisello F, Wertz J, et al.
Circ Res
. 2009 Oct;
105(10):965-72.
PMID: 19797175
Rationale: Fatty acid nitroalkenes are endogenously generated electrophilic byproducts of nitric oxide and nitrite-dependent oxidative inflammatory reactions. Existing evidence indicates nitroalkenes support posttranslational protein modifications and transcriptional activation that promote...
10.
Silvis M, Bertrand C, Ameen N, Golin-Bisello F, Butterworth M, Frizzell R, et al.
Mol Biol Cell
. 2009 Feb;
20(8):2337-50.
PMID: 19244346
The cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP/PKA-activated anion channel, undergoes efficient apical recycling in polarized epithelia. The regulatory mechanisms underlying CFTR recycling are understood poorly, yet this process...