Forrest C Walker
Overview
Explore the profile of Forrest C Walker including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
217
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Recent Articles
1.
Chou-Zheng L, Howell O, Boyle T, Hossain M, Walker F, Sheriff E, et al.
Nucleic Acids Res
. 2024 Nov;
52(22):13490-13514.
PMID: 39551936
Clustered regularly-interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins protect bacteria and archaea from their viruses, and anti-CRISPRs (Acrs) are small virus-encoded proteins that inhibit CRISPR-Cas immunity. Over 80...
2.
Aggarwal S, Walker F, Weagley J, McCune B, Wu X, Schriefer L, et al.
PLoS Pathog
. 2024 May;
20(5):e1011961.
PMID: 38701091
Noroviruses (NoVs) are a leading cause of viral gastroenteritis. Despite global clinical relevance, our understanding of how host factors, such as antiviral cytokines interferons (IFNs), modulate NoV population dynamics is...
3.
Walker F, Derre I
Curr Opin Microbiol
. 2023 Dec;
77:102416.
PMID: 38103413
Chlamydia trachomatis is a common cause of sexually transmitted infections in humans with devastating sequelae. Understanding of disease on all scales, from molecular details to the immunology underlying pathology, is...
4.
Yan H, Walker F, Ali A, Han H, Tan L, Veillon L, et al.
Blood Adv
. 2022 Feb;
6(6):1754-1765.
PMID: 35143611
Antibiotic therapy, especially when administered long term, is associated with adverse hematologic effects such as cytopenia. Signals from the intestinal microbiota are critical to maintain normal hematopoiesis, and antibiotics can...
5.
Lawrence D, Campbell D, Schriefer L, Rodgers R, Walker F, Turkin M, et al.
Gut Microbes
. 2022 Feb;
14(1):2029673.
PMID: 35130125
As our understanding of the importance of the human microbiota in health and disease grows, so does our need to carefully resolve and delineate its genomic content. 16S rRNA gene-based...
6.
Walker F, Sridhar P, Baldridge M
Trends Immunol
. 2021 Oct;
42(11):1009-1023.
PMID: 34629295
Interferons (IFNs) are among the first vertebrate immune pathways activated upon viral infection and are crucial for control of viral replication and dissemination, especially at mucosal surfaces as key locations...
7.
Walker F, Hassan E, Peterson S, Rodgers R, Schriefer L, Thompson C, et al.
PLoS Pathog
. 2021 Mar;
17(3):e1009402.
PMID: 33705489
Interferons (IFNs) are key controllers of viral replication, with intact IFN responses suppressing virus growth and spread. Using the murine norovirus (MNoV) system, we show that IFNs exert selective pressure...
8.
Graziano V, Walker F, Kennedy E, Wei J, Ettayebi K, Strine M, et al.
PLoS Pathog
. 2020 Apr;
16(4):e1008242.
PMID: 32251490
Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. Viral receptor utilization is a major determinant of cell tropism, host range, and...
9.
Walker F, Baldridge M
Curr Opin Virol
. 2019 May;
37:1-9.
PMID: 31096124
In recent years, appreciation has been growing for the role that the microbiota plays in interactions between the host and various pathogens, including norovirus. Proviral and antiviral effects of the...
10.
Nasef M, Muffly M, Beckman A, Rowe S, Walker F, Hatoum-Aslan A, et al.
RNA
. 2019 May;
25(8):948-962.
PMID: 31076459
CRISPR-Cas systems are a class of adaptive immune systems in prokaryotes that use small CRISPR RNAs (crRNAs) in conjunction with CRISPR-associated (Cas) nucleases to recognize and degrade foreign nucleic acids....