Florian Witte
Overview
Explore the profile of Florian Witte including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
353
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Morvan F, Rondeau J, Zou C, Minetti G, Scheufler C, Scharenberg M, et al.
Proc Natl Acad Sci U S A
. 2017 Nov;
114(47):12448-12453.
PMID: 29109273
The TGF-β family ligands myostatin, GDF11, and activins are negative regulators of skeletal muscle mass, which have been reported to primarily signal via the ActRIIB receptor on skeletal muscle and...
2.
Bernatik O, Radaszkiewicz T, Behal M, Dave Z, Witte F, Mahl A, et al.
Front Cell Dev Biol
. 2017 May;
5:47.
PMID: 28523267
Mammalian limb development is driven by the integrative input from several signaling pathways; a failure to receive or a misinterpretation of these signals results in skeletal defects. The brachydactylies, a...
3.
Witte F, Chan D, Economides A, Mundlos S, Stricker S
Proc Natl Acad Sci U S A
. 2010 Jul;
107(32):14211-6.
PMID: 20660756
Elongation of the digit rays resulting in the formation of a defined number of phalanges is a process poorly understood in mammals, whereas in the chicken distal mesenchymal bone morphogenetic...
4.
Witte F, Bernatik O, Kirchner K, Masek J, Mahl A, Krejci P, et al.
FASEB J
. 2010 Mar;
24(7):2417-26.
PMID: 20215527
Dishevelled (Dvl) is a multifunctional effector of different Wnt cascades. Both canonical Wnt3a and noncanonical Wnt5a stimulate casein-kinase-1 (CK1) -mediated phosphorylation of Dvl, visualized as electrophoretic mobility shift [phosphorylated and...
5.
Verhey van Wijk N, Witte F, Feike A, Schambony A, Birchmeier W, Mundlos S, et al.
Biochem Biophys Res Commun
. 2009 Sep;
390(2):211-6.
PMID: 19785987
Wtip is a LIM domain protein of the Ajuba/Zyxin family involved in kidney and neural crest development; Ror2 is a receptor tyrosine kinase involved in the development of skeleton, heart,...
6.
Schwarzer W, Witte F, Rajab A, Mundlos S, Stricker S
Hum Mol Genet
. 2009 Jul;
18(21):4013-21.
PMID: 19640924
Mutations in ROR2 cause dominant brachydactyly type B (BDB1) or recessive Robinow syndrome (RRS), each characterized by a distinct combination of phenotypic features. We here report a novel nonsense mutation...
7.
Gao B, Hu J, Stricker S, Cheung M, Ma G, Law K, et al.
Nature
. 2009 Mar;
458(7242):1196-200.
PMID: 19252479
Brachydactyly type A1 (BDA1) was the first recorded disorder of the autosomal dominant Mendelian trait in humans, characterized by shortened or absent middle phalanges in digits. It is associated with...
8.
Witte F, Dokas J, Neuendorf F, Mundlos S, Stricker S
Gene Expr Patterns
. 2009 Feb;
9(4):215-23.
PMID: 19185060
Wnt signalling plays important roles in patterning and outgrowth of the vertebrate limb. Different mutations in Wnt genes, their antagonists or (co-)receptors result in patterning and outgrowth defects as well...
9.
Kuss P, Villavicencio-Lorini P, Witte F, Klose J, Albrecht A, Seemann P, et al.
J Clin Invest
. 2008 Dec;
119(1):146-56.
PMID: 19075394
Individuals with the birth defect synpolydactyly (SPD) have 1 or more digit duplicated and 2 or more digits fused together. One form of SPD is caused by polyalanine expansions in...
10.
Raz R, Stricker S, Gazzerro E, Clor J, Witte F, Nistala H, et al.
Development
. 2008 Mar;
135(9):1713-23.
PMID: 18353862
Mutations in ROR2 result in a spectrum of genetic disorders in humans that are classified, depending on the nature of the mutation and the clinical phenotype, as either autosomal dominant...