Florian Halbritter
Overview
Explore the profile of Florian Halbritter including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
1614
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Recent Articles
1.
Noorizadeh R, Sax B, Javaheri T, Radic-Sarikas B, Fock V, Suresh V, et al.
Cell Rep
. 2025 Mar;
44(3):115381.
PMID: 40080499
Ewing sarcoma (EwS) is an aggressive cancer of adolescents in need of effective treatment. Insulin-like growth factor (IGF)-1 is an autocrine growth factor for EwS, but only 10% of patients...
2.
Ressler J, Plaschka M, Silmbrod R, Bachmayr V, Shaw L, Silly T, et al.
Nat Cancer
. 2025 Jan;
6(1):51-66.
PMID: 39820126
We present a single-arm, phase II, neoadjuvant trial with the oncolytic virus talimogene laherparepvec (T-VEC) in 18 patients with difficult-to-resect cutaneous basal cell carcinomas. The primary end point, defined as...
3.
Buri M, Shoeb M, Bykov A, Repiscak P, Baik H, Dupanovic A, et al.
Cancer Immunol Res
. 2024 Dec;
13(3):430-446.
PMID: 39642167
The term cancer immunoediting describes the dual role by which the immune system can suppress and promote tumor growth and is divided into three phases: elimination, equilibrium, and escape. The...
4.
BRAFV600E induces key features of LCH in iPSCs with cell type-specific phenotypes and drug responses
Abagnale G, Schwentner R, Ben Soussia-Weiss P, van Midden W, Sturtzel C, Potschger U, et al.
Blood
. 2024 Dec;
145(8):850-865.
PMID: 39630039
Langerhans cell histiocytosis (LCH) is a clonal hematopoietic disorder defined by tumorous lesions containing CD1a+/CD207+ cells. Two severe complications of LCH are systemic hyperinflammation and progressive neurodegeneration. The scarcity of...
5.
Ransmayr B, Bal S, Thian M, Svaton M, van de Wetering C, Hafemeister C, et al.
Sci Immunol
. 2024 Nov;
9(101):eadq8796.
PMID: 39576873
Secondary lymphoid organs (SLOs) provide the confined microenvironment required for stromal cells to interact with immune cells to initiate adaptive immune responses resulting in B cell differentiation. Here, we studied...
6.
Saldana-Guerrero I, Montano-Gutierrez L, Boswell K, Hafemeister C, Poon E, Shaw L, et al.
Nat Commun
. 2024 May;
15(1):3745.
PMID: 38702304
Early childhood tumours arise from transformed embryonic cells, which often carry large copy number alterations (CNA). However, it remains unclear how CNAs contribute to embryonic tumourigenesis due to a lack...
7.
Fortelny N, Farlik M, Fife V, Gorki A, Lassnig C, Maurer B, et al.
Nat Immunol
. 2024 Apr;
25(5):847-859.
PMID: 38658806
Immune cells need to sustain a state of constant alertness over a lifetime. Yet, little is known about the regulatory processes that control the fluent and fragile balance that is...
8.
Kirchberger S, Shoeb M, Lazic D, Wenninger-Weinzierl A, Fischer K, Shaw L, et al.
Nat Commun
. 2024 Feb;
15(1):1792.
PMID: 38413586
Neutrophils are evolutionarily conserved innate immune cells playing pivotal roles in host defense. Zebrafish models have contributed substantially to our understanding of neutrophil functions but similarities to human neutrophil maturation...
9.
Karwacki-Neisius V, Jang A, Cukuroglu E, Tai A, Jiao A, Predes D, et al.
Nature
. 2024 Feb;
627(8004):594-603.
PMID: 38383780
Although KDM5C is one of the most frequently mutated genes in X-linked intellectual disability, the exact mechanisms that lead to cognitive impairment remain unknown. Here we use human patient-derived induced...
10.
Bal S, Giuliani S, Block J, Repiscak P, Hafemeister C, Shahin T, et al.
Blood
. 2023 May;
142(9):827-845.
PMID: 37249233
The nuclear factor of activated T cells (NFAT) family of transcription factors plays central roles in adaptive immunity in murine models; however, their contribution to human immune homeostasis remains poorly...