Florian Gaertner
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Explore the profile of Florian Gaertner including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
1124
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Recent Articles
1.
Fan S, Raude B, Gaertner F
J Vis Exp
. 2024 Nov;
(213).
PMID: 39584677
Despite being anucleated cell fragments, platelets are now widely recognized for their multifaceted abilities. Not only do they form blood clots to prevent bleeding after injury, but they also fight...
2.
Stark K, Kilani B, Stockhausen S, Busse J, Schubert I, Tran T, et al.
Immunity
. 2024 Sep;
57(9):2140-2156.e10.
PMID: 39226900
Venous thromboembolism (VTE) is a common, deadly disease with an increasing incidence despite preventive efforts. Clinical observations have associated elevated antibody concentrations or antibody-based therapies with thrombotic events. However, how...
3.
Gaertner F, Ishikawa-Ankerhold H, Stutte S, Fu W, Weitz J, Dueck A, et al.
Nature
. 2024 Jul;
631(8021):645-653.
PMID: 38987596
Platelet homeostasis is essential for vascular integrity and immune defence. Although the process of platelet formation by fragmenting megakaryocytes (MKs; thrombopoiesis) has been extensively studied, the cellular and molecular mechanisms...
4.
Gaertner F, Preissner S, Heiland M, Preissner R, Wuster J
Cancers (Basel)
. 2024 Mar;
16(5).
PMID: 38473343
Introduction: Even in times of new therapy regimes, the overall survival of patients with head and neck cancer remains low. Since the previous studies showed the beneficial effect of metformin...
5.
Sisario D, Spindler M, Ermer K, Grutz N, Nicolai L, Gaertner F, et al.
Cells
. 2024 Feb;
13(4.
PMID: 38391912
Platelet function at vascular injury sites is tightly regulated through the actin cytoskeleton. The Wiskott-Aldrich syndrome protein-family verprolin-homologous protein (WAVE)-regulatory complex (WRC) activates lamellipodia formation via ARP2/3, initiated by GTP-bound...
6.
Gaertner F, Preissner S, Petri Jr W, Atolani O, Heiland M, Nahles S, et al.
BMC Infect Dis
. 2023 Sep;
23(1):610.
PMID: 37723464
Background: The course of monkeypox can be severe. Our aim was to retrospectively compare the risk of hospital admission, the need for ventilation, sepsis, pneumonitis and death between the recent...
7.
Kahn S, Arnold D, Casari C, Desch K, Devreese K, Favaloro E, et al.
Res Pract Thromb Haemost
. 2023 Aug;
7(4):100193.
PMID: 37538494
This year's Congress of the International Society of Thrombosis and Haemostasis (ISTH) took place in person in Montréal, Canada, from June 24-28, 2023. The conference, held annually, highlighted cutting-edge advances...
8.
Kaiser R, Anjum A, Kammerer L, Loew Q, Akhalkatsi A, Rossaro D, et al.
Blood
. 2023 Apr;
141(24):2973-2992.
PMID: 37018659
Platelets are not only the first responders in thrombosis and hemostasis but also central players in inflammation. Compared with platelets recruited to thrombi, immune-responsive platelets use distinct effector functions including...
9.
Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease
Petzold T, Zhang Z, Ballesteros I, Saleh I, Polzin A, Thienel M, et al.
Immunity
. 2022 Oct;
55(12):2285-2299.e7.
PMID: 36272416
Intravascular neutrophils and platelets collaborate in maintaining host integrity, but their interaction can also trigger thrombotic complications. We report here that cooperation between neutrophil and platelet lineages extends to the...
10.
Nicolai L, Schiefelbein K, Lipsky S, Leunig A, Hoffknecht M, Pekayvaz K, et al.
Nat Commun
. 2022 Aug;
13(1):4645.
PMID: 35941111
No abstract available.