Florian Gaertner
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Explore the profile of Florian Gaertner including associated specialties, affiliations and a list of published articles.
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34
Citations
1124
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Recent Articles
11.
Kaiser R, Escaig R, Kranich J, Hoffknecht M, Anjum A, Polewka V, et al.
Blood
. 2022 Apr;
140(2):121-139.
PMID: 35472164
Impairment of vascular integrity is a hallmark of inflammatory diseases. We recently reported that single immune-responsive platelets migrate and reposition themselves to sites of vascular injury to prevent bleeding. However,...
12.
Gaertner F, Reis-Rodrigues P, de Vries I, Hons M, Aguilera J, Riedl M, et al.
Dev Cell
. 2021 Dec;
57(1):47-62.e9.
PMID: 34919802
When crawling through the body, leukocytes often traverse tissues that are densely packed with extracellular matrix and other cells, and this raises the question: How do leukocytes overcome compressive mechanical...
13.
Single platelet and megakaryocyte morpho-dynamics uncovered by multicolor reporter mouse strains and
Nicolai L, Kaiser R, Escaig R, Hoffknecht M, Anjum A, Leunig A, et al.
Haematologica
. 2021 Sep;
107(7):1669-1680.
PMID: 34525794
Visualizing cell behavior and effector function on a single cell level has been crucial for understanding key aspects of mammalian biology. Due to their small size, large number and rapid...
14.
Fan S, Lorenz M, Massberg S, Gaertner F
Bio Protoc
. 2021 Aug;
8(18):e3018.
PMID: 34395806
Blood platelets are critical for hemostasis and thrombosis, but also play diverse roles during immune responses. We have recently reported that platelets migrate at sites of infection and Importantly, platelets...
15.
Gaertner F, Sixt M
Dev Cell
. 2021 Mar;
56(6):723-725.
PMID: 33756118
In this issue of Developmental Cell, Doyle and colleagues identify periodic anterior contraction as a characteristic feature of fibroblasts and mesenchymal cancer cells embedded in 3D collagen gels. This contractile...
16.
Nicolai L, Schiefelbein K, Lipsky S, Leunig A, Hoffknecht M, Pekayvaz K, et al.
Nat Commun
. 2020 Nov;
11(1):5778.
PMID: 33188196
Breakdown of vascular barriers is a major complication of inflammatory diseases. Anucleate platelets form blood-clots during thrombosis, but also play a crucial role in inflammation. While spatio-temporal dynamics of clot...
17.
Reversat A, Gaertner F, Merrin J, Stopp J, Tasciyan S, Aguilera J, et al.
Nature
. 2020 Jun;
582(7813):582-585.
PMID: 32581372
Eukaryotic cells migrate by coupling the intracellular force of the actin cytoskeleton to the environment. While force coupling is usually mediated by transmembrane adhesion receptors, especially those of the integrin...
18.
Nicolai L, Gaertner F, Massberg S
Trends Immunol
. 2019 Oct;
40(10):922-938.
PMID: 31601520
Platelets are central players in thrombosis and hemostasis but are increasingly recognized as key components of the immune system. They shape ensuing immune responses by recruiting leukocytes, and support the...
19.
Gaertner F, Massberg S
Nat Rev Immunol
. 2019 Aug;
19(12):747-760.
PMID: 31409920
Platelets are small anucleate cellular fragments that are released by megakaryocytes and safeguard vascular integrity through a process termed 'haemostasis'. However, platelets have important roles beyond haemostasis as they contribute...
20.
Heinzel A, Boghos D, Mottaghy F, Gaertner F, Essler M, von Mallek D, et al.
Eur J Nucl Med Mol Imaging
. 2019 Jan;
46(5):1054-1062.
PMID: 30697649
Purpose: To evaluate the use of Ga-PSMA PET/CT for monitoring response to Lu-617 PSMA radioligand therapy in patients with metastatic castrate-resistant prostate cancer (mCRPC). Methods: Patients from the University Hospital...