Florian Freudenberg
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Explore the profile of Florian Freudenberg including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
283
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Recent Articles
1.
Freudenberg F, Reif-Leonhard C, Reif A
Eur Arch Psychiatry Clin Neurosci
. 2024 Aug;
PMID: 39207462
Changes in glutamatergic neuroplasticity has been proposed as one of the core mechanisms underlying the pathophysiology of depression. In consequence components of the glutamatergic synapse have been explored as potential...
2.
Yotova A, Li L, OLeary A, Tegeder I, Reif A, Courtney M, et al.
Brain Behav Immun
. 2024 Aug;
121:351-364.
PMID: 39089536
Background: Maternal immune activation (MIA) triggers neurobiological changes in offspring, potentially reshaping the molecular synaptic landscape, with the hippocampus being particularly vulnerable. However, critical details regarding developmental timing of these...
3.
Vogel A, Ueberbach T, Wilken-Schmitz A, Hahnefeld L, Franck L, Weyer M, et al.
Cell Biosci
. 2023 Aug;
13(1):155.
PMID: 37635256
Background: Pain in early life may impact on development and risk of chronic pain. We developed an optogenetic Cre/loxP mouse model of "early-life-pain" (ELP) using mice with transgenic expression of...
4.
Yotova A, Li L, OLeary A, Tegeder I, Reif A, Courtney M, et al.
Res Sq
. 2023 Jul;
PMID: 37461513
Maternal infections during pregnancy pose an increased risk for neurodevelopmental psychiatric disorders (NPDs) in the offspring. Here, we examined age- and sex-dependent dynamic changes of the hippocampal synaptic proteome after...
5.
Candemir E, Fattakhov N, Leary A, Slattery D, Courtney M, Reif A, et al.
Eur Neuropsychopharmacol
. 2022 Dec;
67:66-79.
PMID: 36513018
The neuronal isoform of nitric oxide synthase (nNOS) and its interacting protein NOS1AP have been linked to several mental disorders including schizophrenia and depression. An increase in the interaction between...
6.
Freudenberg F, Althen H, Falk K, Bittner R, Reif A, Plichta M
Acta Neuropsychiatr
. 2022 Aug;
34(6):344-353.
PMID: 35959694
Objective: Sensorimotor gating is experimentally operationalized by the prepulse inhibition (PPI) of the startle response (SR). Previous studies suggest high test-retest reliability of PPI and potential correlation with working memory...
7.
OLeary A, Fernandez-Castillo N, Gan G, Yang Y, Yotova A, Kranz T, et al.
Mol Psychiatry
. 2022 Aug;
27(11):4464-4473.
PMID: 35948661
Common variation in the gene encoding the neuron-specific RNA splicing factor RNA Binding Fox-1 Homolog 1 (RBFOX1) has been identified as a risk factor for several psychiatric conditions, and rare...
8.
Esen-Sehir D, Kopf J, Hagele S, Plichta M, Reif A, Freudenberg F
Pharmacopsychiatry
. 2022 Jun;
55(5):266-273.
PMID: 35732169
Introduction: The variants of the gene for nitric oxide synthase 1 adaptor protein () are associated with schizophrenia and cardiovascular deficits involving corrected QT (QTc) interval prolongation. Here, we investigated...
9.
McNeill R, Kehrwald C, Brum M, Knopf K, Brunkhorst-Kanaan N, Etyemez S, et al.
Brain Behav Immun
. 2022 Jan;
101:275-283.
PMID: 35041938
Nitric oxide (NO) signalling has been implicated in the pathogenesis of several mental illnesses; however, its specific contribution remains unclear. We investigated whether peripheral NO concentration is associated with specific...
10.
Freudenberg F, Candemir E, Chen X, Li L, Esen-Sehir D, Schenk N, et al.
EBioMedicine
. 2021 Aug;
71:103565.
PMID: 34455393
Background: Nitric oxide synthase 1 adaptor protein (NOS1AP; previously named CAPON) is linked to the glutamatergic postsynaptic density through interaction with neuronal nitric oxide synthase (nNOS). NOS1AP and its interaction...