Florent Chuffart
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Explore the profile of Florent Chuffart including associated specialties, affiliations and a list of published articles.
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32
Citations
298
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Recent Articles
1.
Dumolard L, Gerster T, Chuffart F, Decaens T, Hilleret M, Larrat S, et al.
Hepatol Commun
. 2025 Jan;
9(2).
PMID: 39878655
Background: Hepatitis B is a liver infection caused by HBV. Infected individuals who fail to control the viral infection develop chronic hepatitis B and are at risk of developing life-threatening...
2.
Montellier E, Lemonnier N, Penkert J, Freycon C, Blanchet S, Amadou A, et al.
iScience
. 2024 Dec;
27(12):111296.
PMID: 39634561
Li-Fraumeni syndrome (LFS) is a heterogeneous predisposition to an individually variable spectrum of cancers caused by pathogenic germline variants. We used a clustering method to assign TP53 missense variants to...
3.
Gaucher J, Montellier E, Vial G, Chuffart F, Guellerin M, Bouyon S, et al.
iScience
. 2024 Feb;
27(2):108837.
PMID: 38303705
Obstructive sleep apnea (OSA) induces intermittent hypoxia (IH), an independent risk factor for non-alcoholic fatty liver disease (NAFLD). While the molecular links between IH and NAFLD progression are unclear, immune...
4.
Iuso D, Garcia-Saez I, Coute Y, Yamaryo-Botte Y, Boeri Erba E, Adrait A, et al.
Sci Adv
. 2023 Sep;
9(36):eadh0140.
PMID: 37672589
The synthesis of fatty acids from acetyl-coenzyme A (AcCoA) is deregulated in diverse pathologies, including cancer. Here, we report that fatty acid accumulation is negatively regulated by nucleoside diphosphate kinases...
5.
Jacquet E, Chuffart F, Vitte A, Nika E, Mousseau M, Khochbin S, et al.
BMC Genomics
. 2023 Aug;
24(1):463.
PMID: 37592220
Background: In breast cancer, as in all cancers, genetic and epigenetic deregulations can result in out-of-context expressions of a set of normally silent tissue-specific genes. The activation of some of...
6.
Castillo-Ferrer C, Marguet T, Vanwonterghem L, Erbek S, Chuffart F, Mouret S, et al.
J Invest Dermatol
. 2023 Aug;
144(2):422-426.e8.
PMID: 37580013
No abstract available.
7.
Timcheva K, Dufour S, Touat-Todeschini L, Burnard C, Carpentier M, Chuffart F, et al.
Cell Rep
. 2022 Dec;
41(11):111784.
PMID: 36516773
Heat stress (HS) induces a cellular response leading to profound changes in gene expression. Here, we show that human YTHDC1, a reader of N-methyladenosine (mA) RNA modification, mostly associates to...
8.
Mathieu M, Friedrich C, Ducrot N, Zannoni J, Sylvie T, Jerraya N, et al.
Ann Hematol
. 2022 Oct;
101(12):2633-2643.
PMID: 36195681
In low-risk myelodysplastic syndrome (LR-MDS), erythropoietin (EPO) is widely used for the treatment of chronic anemia. However, initial response to EPO has time-limited effects. Luspatercept reduces red blood cell transfusion...
9.
Lukinovic V, Hausmann S, Roth G, Oyeniran C, Ahmad T, Tsao N, et al.
Cancer Discov
. 2022 Jul;
12(9):2158-2179.
PMID: 35819319
Significance: SCLC rapidly becomes resistant to conventional chemotherapy, leaving patients with no alternative treatment options. Our data demonstrate that SMYD3 upregulation and RNF113A methylation in SCLC are key mechanisms that...
10.
Carreres L, Mercey-Ressejac M, Kurma K, Ghelfi J, Fournier C, Manches O, et al.
Cells
. 2022 Jul;
11(13).
PMID: 35805134
Obstructive sleep apnea (OSA) syndrome is characterized by chronic intermittent hypoxia and is associated with an increased risk of all-cause mortality, including cancer mortality. Hepatocellular carcinoma (HCC) is the most...