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Floortje L Kessler

Explore the profile of Floortje L Kessler including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 168
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Recent Articles
1.
van Gils N, Verhagen H, Rutten A, Menezes R, Tsui M, Vermue E, et al.
Blood Adv . 2020 Dec; 4(24):6368-6383. PMID: 33351133
Treatment of acute promyelocytic leukemia (APL) with all-trans retinoic acid (ATRA) in combination with low doses of arsenic trioxide or chemotherapy leads to exceptionally high cure rates (>90%). ATRA forces...
2.
Franke N, Kaspers G, Assaraf Y, Van Meerloo J, Niewerth D, Kessler F, et al.
Oncotarget . 2016 Aug; 7(46):74779-74796. PMID: 27542283
PSMB5 mutations and upregulation of the β5 subunit of the proteasome represent key determinants of acquired resistance to the proteasome inhibitor bortezomib (BTZ) in leukemic cells in vitro. We here...
3.
Wojtuszkiewicz A, Schuurhuis G, Kessler F, Piersma S, Knol J, Pham T, et al.
Mol Cell Proteomics . 2016 Jan; 15(4):1281-98. PMID: 26801919
Expression of apoptosis-regulating proteins (B-cell CLL/lymphoma 2 - BCL-2, Myeloid Cell Leukemia 1 - MCL-1, BCL-2 like 1 - BCL-X and BCL-2-associated X protein - BAX) in acute myeloid leukemia...
4.
Zweegman S, Kessler F, Celie J, Janssen J, van den Born J, Schuurhuis G, et al.
Blood . 2009 Dec; 114(26):5404-6. PMID: 20018929
No abstract available.
5.
Celie J, Rutjes N, Keuning E, Soininen R, Heljasvaara R, Pihlajaniemi T, et al.
Am J Pathol . 2007 May; 170(6):1865-78. PMID: 17525255
Leukocyte infiltration into inflamed tissues is considered to involve sequential steps of rolling over the endothelium, adhesion, and transmigration. In this model, the leukocyte adhesion molecule L-selectin and its ligands...
6.
Zweegman S, Kessler F, Kerkhoven R, Heimerikx M, Celie J, Janssen J, et al.
Matrix Biol . 2007 May; 26(7):561-71. PMID: 17521897
High dose chemotherapy and radiation have been found to impair the hematopoiesis-supportive capacity of bone marrow stroma. We now provide evidence for an important role of chemotherapy-induced alterations in stromal...
7.
Celie J, Keuning E, Beelen R, Drager A, Zweegman S, Kessler F, et al.
J Biol Chem . 2005 May; 280(29):26965-73. PMID: 15917223
L-selectin is a C-type lectin expressed on leukocytes that is involved in both lymphocyte homing to the lymph node and leukocyte extravasation during inflammation. Known L-selectin ligands include sulfated Lewis-type...
8.
Zweegman S, Van Den Born J, Mus A, Kessler F, Janssen J, Netelenbos T, et al.
Exp Cell Res . 2004 Sep; 299(2):383-92. PMID: 15350537
Adherence of hematopoietic progenitor cells (HPCs) to stroma is an important regulatory step in megakaryocytic differentiation. However, the mechanisms through which megakaryocytic progenitors are inhibited by stroma are poorly understood....
9.
Netelenbos T, van den Born J, Kessler F, Zweegman S, Huijgens P, Drager A
J Leukoc Biol . 2003 Oct; 74(6):1035-44. PMID: 14525970
Proteoglycans (PGs) play a dominant role within the bone marrow (BM), but their role in homing of transplanted hematopoietic progenitor cells (HPC) is unknown. In this study, the role of...
10.
de Boer F, Drager A, Pinedo H, Kessler F, Monnee-van Muijen M, Weijers G, et al.
J Hematother Stem Cell Res . 2003 Feb; 11(6):951-63. PMID: 12590710
Quality assessment of stem cell grafts is usually performed by flow cytometric CD34(+) enumeration or assessment of clonogenic output of fresh material. Previously, we identified the occurrence of early apoptosis,...