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Flavia Ferrantelli

Explore the profile of Flavia Ferrantelli including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 653
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Recent Articles
1.
Ferrantelli F, Manfredi F, Donnini M, Leone P, Pugliese K, Olivetta E, et al.
Cancer Gene Ther . 2024 Sep; 31(11):1688-1695. PMID: 39300218
We previously developed an innovative strategy to induce CD8 T lymphocyte-immunity through in vivo engineering of extracellular vesicles (EVs). This approach relies on intramuscular injection of DNA expressing antigens of...
2.
Ferrantelli F, Manfredi F, Chiozzini C, Leone P, Pugliese K, Spada M, et al.
Vaccines (Basel) . 2023 Sep; 11(9). PMID: 37766110
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 enters the host by infecting nasal ciliated cells. Then, the virus can spread towards the oropharyngeal cavity and the pulmonary tissues. The antiviral adaptive...
3.
Manfredi F, Chiozzini C, Ferrantelli F, Leone P, Pugliese K, Spada M, et al.
NPJ Vaccines . 2023 Jun; 8(1):83. PMID: 37268624
Induction of effective immunity in the lungs should be a requisite for any vaccine designed to control the severe pathogenic effects generated by respiratory infectious agents. We recently provided evidence...
4.
Manfredi F, Chiozzini C, Ferrantelli F, Leone P, Giovannelli A, Sanchez M, et al.
Vaccines (Basel) . 2022 Jul; 10(7). PMID: 35891224
We propose an innovative anti-SARS-CoV-2 immune strategy based on extracellular vesicles (EVs) inducing an anti-SARS-CoV-2 N CD8 T cytotoxic lymphocyte (CTL) immune response. We previously reported that the SARS-CoV-2 N...
5.
Ferrantelli F, Tirelli V, Barreca V, Manfredi F
Methods Mol Biol . 2022 Apr; 2504:207-217. PMID: 35467289
Extracellular vesicles (EVs) are membranous particles released by all cells in the external milieu. Depending on their origin, they are given different names: exosomes are nanovesicles that originate from the...
6.
Ferrantelli F, Chiozzini C, Manfredi F, Leone P, Spada M, Di Virgilio A, et al.
Viruses . 2022 Feb; 14(2). PMID: 35215922
SARS-CoV-2-specific CD8 T cell immunity is expected to counteract viral variants in both efficient and durable ways. We recently described a way to induce a potent SARS-CoV-2 CD8 T immune...
7.
Ferrantelli F, Manfredi F, Chiozzini C, Leone P, Giovannelli A, Olivetta E, et al.
Cancers (Basel) . 2021 Jun; 13(9). PMID: 34066801
We developed an innovative method to induce antigen-specific CD8 T cytotoxic lymphocyte (CTL) immunity based on in vivo engineering of extracellular vesicles (EVs). This approach employs a DNA vector expressing...
8.
Chiozzini C, Manfredi F, Ferrantelli F, Leone P, Giovannelli A, Olivetta E, et al.
Vaccines (Basel) . 2021 Apr; 9(4). PMID: 33921215
Intramuscular injection of DNA vectors expressing the extracellular vesicle (EV)-anchoring protein Nef fused at its C-terminus to viral and tumor antigens elicit a potent, effective, and anti-tolerogenic CD8 T cell...
9.
Ferrantelli F, Chiozzini C, Manfredi F, Giovannelli A, Leone P, Federico M
Vaccines (Basel) . 2021 Apr; 9(3). PMID: 33801926
Most advanced vaccines against severe acute respiratory syndrome coronavirus (SARS-CoV)-2 are designed to induce antibodies against spike (S) protein. Differently, we developed an original strategy to induce CD8 T cytotoxic...
10.
Fiani M, Barreca V, Sargiacomo M, Ferrantelli F, Manfredi F, Federico M
Int J Mol Sci . 2020 Sep; 21(17). PMID: 32878276
Immunosuppression at tumor microenvironment (TME) is one of the major obstacles to be overcome for an effective therapeutic intervention against solid tumors. Tumor-associated macrophages (TAMs) comprise a sub-population that plays...