Fiona D Zeeb
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Explore the profile of Fiona D Zeeb including associated specialties, affiliations and a list of published articles.
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24
Citations
867
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Recent Articles
1.
Russell B, Hrelja K, Adams W, Zeeb F, Taves M, Kaur S, et al.
Behav Brain Res
. 2022 Jul;
433:114000.
PMID: 35817135
Social isolation is an established risk factor for mental illness and impaired immune function. Evidence suggests that neuroinflammatory processes contribute to mental illness, possibly via cytokine-induced modulation of neural activity....
2.
Fugariu V, Zack M, Nobrega J, Fletcher P, Zeeb F
Neuropsychopharmacology
. 2020 Jan;
45(5):811-822.
PMID: 31905371
Gambling disorder (GD) is a behavioral addiction that may be linked to alterations in dopamine (DA) systems. Gambling involves chronic exposure to uncertain reward, which can sensitize the activity of...
3.
Higgins G, Silenieks L, MacMillan C, Zeeb F, Thevarkunnel S
Behav Brain Res
. 2018 Apr;
348:201-210.
PMID: 29689373
Previous studies demonstrated that NMDA receptor antagonists such as dizocilpine (MK801) and the GluN2B NMDA antagonist Ro 63-1908 promote impulsive action (motor impulsivity). The effects of these treatments on impulsive...
4.
Higgins G, Zeeb F, Fletcher P
J Psychopharmacol
. 2017 Oct;
31(11):1403-1418.
PMID: 29072522
The selective 5-HT receptor agonist lorcaserin entered clinical obesity trials with the prevalent view that satiety was a primary mechanism of action. Subsequent Phase II and III trials demonstrated efficacy...
5.
Zeeb F, Li Z, Fisher D, Zack M, Fletcher P
J Psychiatry Neurosci
. 2017 Aug;
42(6):404-413.
PMID: 28832319
Background: An animal model of gambling disorder, previously known as pathological gambling, could advance our understanding of the disorder and help with treatment development. We hypothesized that repeated exposure to...
6.
Adams W, Barrus M, Zeeb F, Cocker P, Benoit J, Winstanley C
Behav Brain Res
. 2017 Mar;
328:19-27.
PMID: 28344096
The α-adrenoceptor antagonist, yohimbine, is commonly used as a pharmacological stressor. Its behavioural effects are typically attributed to elevated noradrenaline release via blockade of central, inhibitory autoreceptors. We have previously...
7.
Fletcher P, Zeeb F, Browne C, Higgins G, Soko A
Psychopharmacology (Berl)
. 2017 Jan;
234(5):889-902.
PMID: 28097374
Objectives: These experiments examined the effects of selective 5-HT, 5-HT and 5-HT receptor ligands on responding for a conditioned reinforcer (CRf). Effects of these ligands were measured under basal conditions...
8.
Higgins G, Silenieks L, MacMillan C, Sevo J, Zeeb F, Thevarkunnel S
Behav Brain Res
. 2016 May;
311:1-14.
PMID: 27180168
NMDA GluN2B (NR2B) subtype selective antagonists are currently in clinical development for a variety of indications, including major depression. We previously reported the selective NMDA GluN2B antagonists Ro 63-1908 and...
9.
Zeeb F, Soko A, Ji X, Fletcher P
Neuropsychopharmacology
. 2016 Jan;
41(8):2091-100.
PMID: 26781518
Poor impulse control is associated with an increased propensity to develop an addiction and may contribute to relapse as high impulsive subjects appear to attribute greater salience toward drug-paired stimuli....
10.
Browne C, Fletcher P, Zeeb F
Psychopharmacology (Berl)
. 2015 Dec;
233(6):983-93.
PMID: 26690588
Rationale: Environmental factors influence the etiology of many psychiatric disorders. Likewise, environmental factors can alter processes central to motivation. Therefore, motivational deficits present in many disorders may be influenced by...