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Fiona Chapman

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Articles 14
Citations 69
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Recent Articles
1.
Cordery S, Thompson K, Stevenson M, Simms L, Chapman F, Grandolfo E, et al.
Cureus . 2024 Jun; 16(5):e61223. PMID: 38939262
Heated tobacco products represent a novel category of tobacco products in which a tobacco consumable is heated to a temperature that releases nicotine from the tobacco leaf but not to...
2.
Chapman F, de Haan L, Gijzen L, Strijker W, Sticken E, Pour S, et al.
Front Toxicol . 2024 Jun; 6:1395670. PMID: 38938662
Background: Smoking cigarettes is a cause of serious diseases in smokers, including cardiovascular disease. Through a pathway of endothelial dysfunction, lipid infiltration, macrophage recruitment and vascular remodeling, atherosclerosis is fundamental...
3.
Moreau M, Simms L, Andersen M, Sticken E, Wieczorek R, Pour S, et al.
Front Toxicol . 2024 Apr; 6:1373325. PMID: 38665213
With the use of new approach methodologies (NAMs) for the assessment of non-combustible next-generation nicotine delivery products, new extrapolation methods will also be required to interpret and contextualize the physiological...
4.
Chapman F, Pour S, Wieczorek R, Sticken E, Budde J, Rower K, et al.
Front Toxicol . 2023 Mar; 5:1076752. PMID: 36875887
Tobacco harm reduction (THR) involves providing adult smokers with potentially reduced harm modes of nicotine delivery as alternatives to smoking combustible cigarettes. Heated tobacco products (HTPs) form a category with...
5.
Wieczorek R, Sticken E, Pour S, Chapman F, Rower K, Otte S, et al.
J Appl Toxicol . 2023 Feb; 43(7):1050-1063. PMID: 36734622
In vitro testing is important to characterise biological effects of consumer products, including nicotine delivery products such as cigarettes, e-cigarettes and heated tobacco products. Users' cells are exposed to these...
6.
Bankoglu E, Chapman F, Geric M
Mutagenesis . 2022 Dec; 38(1):1-2. PMID: 36512390
No abstract available.
7.
Chapman F, Sticken E, Wieczorek R, Pour S, Dethloff O, Budde J, et al.
Toxicol In Vitro . 2022 Nov; 86:105510. PMID: 36372310
This study aimed to compare the aerosol chemistry and in vitro toxicological profiles of two prototype Heated Tobacco Product (p-HTP) variants to the 1R6F Reference Cigarette. In the neutral red...
8.
Chapman F, McDermott S, Rudd K, Taverner V, Stevenson M, Chaudhary N, et al.
Psychopharmacology (Berl) . 2022 Jun; 239(9):2931-2943. PMID: 35732751
Rationale: Tobacco harm reduction (THR) involves encouraging adult smokers who would otherwise continue to smoke to transition to less harmful forms of nicotine delivery. These products must offer adult smokers...
9.
Simms L, Yu F, Palmer J, Rudd K, Sticken E, Wieczorek R, et al.
Front Toxicol . 2022 Mar; 4:747508. PMID: 35295225
Combustible cigarette smoking is an established risk factor for cardiovascular disease. By contrast, the cardiotoxicity potential of non-combustible next generation nicotine products (NGPs), which includes heated tobacco products (HTPs) and...
10.
Morris P, McDermott S, Chapman F, Verron T, Cahours X, Stevenson M, et al.
Intern Emerg Med . 2021 Aug; 17(2):397-410. PMID: 34435305
Electronic nicotine delivery systems (ENDS) offer adult combustible cigarette smokers an alternative, potentially reduced harm, mode of nicotine delivery, attributed to fewer and reduced levels of harmful and potentially harmful...