Finn Werner
Overview
Explore the profile of Finn Werner including associated specialties, affiliations and a list of published articles.
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Articles
72
Citations
1800
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0
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Recent Articles
1.
Arnvig K, Werner F
Structure
. 2025 Feb;
33(2):213-215.
PMID: 39919710
In this issue of Structure, Dikunova et al. report the structure of the trimeric torpedo complex, the key factor responsible for transcription termination by RNA polymerase II R(NAPII) at the...
2.
Phung D, Pilotto S, Matelska D, Blombach F, Pinotsis N, Hovan L, et al.
Structure
. 2024 Nov;
33(1):149-159.e6.
PMID: 39504966
N-utilization substance A (NusA) is a regulatory factor with pleiotropic functions in gene expression in bacteria. Archaea encode two conserved small proteins, NusA1 and NusA2, with domains orthologous to the...
3.
Blombach F, Werner F
Mol Microbiol
. 2024 Aug;
123(3):218-231.
PMID: 39096085
The chromatinisation of DNA by nucleoid-associated proteins (NAPs) in archaea 'formats' the genome structure in profound ways, revealing both striking differences and analogies to eukaryotic chromatin. However, the extent to...
4.
Cackett G, Sykora M, Portugal R, Dulson C, Dixon L, Werner F
Front Immunol
. 2024 Mar;
15:1350267.
PMID: 38545109
Introduction: African swine fever virus (ASFV) is a nucleocytoplasmic large DNA virus (NCLDV) that encodes its own host-like RNA polymerase (RNAP) and factors required to produce mature mRNA. The formation...
5.
Blombach F, Sykora M, Case J, Feng X, Baquero D, Fouqueau T, et al.
Nat Commun
. 2024 Feb;
15(1):1620.
PMID: 38388540
CRISPR arrays form the physical memory of CRISPR adaptive immune systems by incorporating foreign DNA as spacers that are often AT-rich and derived from viruses. As promoter elements such as...
6.
Pilotto S, Sykora M, Cackett G, Dulson C, Werner F
Nat Commun
. 2024 Feb;
15(1):1606.
PMID: 38383525
African Swine Fever Virus is a Nucleo-Cytoplasmic Large DNA Virus that causes an incurable haemorrhagic fever in pigs with a high impact on global food security. ASFV replicates in the...
7.
Ofer S, Blombach F, Erkelens A, Barker D, Soloviev Z, Schwab S, et al.
Commun Biol
. 2023 Sep;
6(1):968.
PMID: 37740023
In eukaryotes, histone paralogues form obligate heterodimers such as H3/H4 and H2A/H2B that assemble into octameric nucleosome particles. Archaeal histones are dimeric and assemble on DNA into 'hypernucleosome' particles of...
8.
Wohnke E, Cackett G, Werner F, Blome S, Mettenleiter T, Karger A
Viruses
. 2022 Oct;
14(10).
PMID: 36298696
Since the introduction of a highly pathogenic genotype II isolate of the African swine fever virus (ASFV) into Georgia in 2007, African swine fever (ASF) has gone panzootic. Outbreaks have...
9.
Han Y, Kinfu B, Blombach F, Cackett G, Zhang H, Perez-Garcia P, et al.
Sci Rep
. 2022 Oct;
12(1):17882.
PMID: 36284144
The mining of genomes from non-cultivated microorganisms using metagenomics is a powerful tool to discover novel proteins and other valuable biomolecules. However, function-based metagenome searches are often limited by the...
10.
Pinna S, Kunz C, Halpern A, Harrison S, Jordan S, Ward J, et al.
PLoS Biol
. 2022 Oct;
20(10):e3001437.
PMID: 36194581
ATP is universally conserved as the principal energy currency in cells, driving metabolism through phosphorylation and condensation reactions. Such deep conservation suggests that ATP arose at an early stage of...