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Filippo Ingoglia

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Citations 128
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Recent Articles
1.
Ingoglia F, Tanfous M, Ellezam B, Anderson K, Pasquali M, Botto L
Mol Genet Metab Rep . 2024 Sep; 41:101142. PMID: 39318848
Multiple acyl-CoA dehydrogenase deficiency (MADD) is a primary mitochondrial dysfunction affecting mitochondrial fatty acid and protein metabolism, caused by biallelic pathogenic variants in ETFA, ETFB, or ETFDH genes. The heterogeneous...
2.
Ingoglia F, Chong J, Pasquali M, Longo N
Mol Genet Metab Rep . 2021 Sep; 29:100791. PMID: 34471603
The urea cycle generates arginine that is one of the major precursors for creatine biosynthesis. Here we evaluate levels of creatine and guanidinoacetate (the precursor in the synthesis of creatine)...
3.
Rotoli B, Barilli A, Ingoglia F, Visigalli R, Bianchi M, Ferrari F, et al.
Orphanet J Rare Dis . 2019 Mar; 14(1):63. PMID: 30832686
Background: y+LAT1, encoded by SCL7A7, is the protein mutated in Lysinuric Protein Intolerance (LPI), a rare metabolic disease caused by a defective cationic amino acid (CAA, arginine, lysine, ornithine) transport...
4.
Rotoli B, Barilli A, Visigalli R, Ingoglia F, Milioli M, Di Lascia M, et al.
Front Immunol . 2018 Apr; 9:508. PMID: 29616026
Lysinuric protein intolerance (LPI) is a recessively inherited aminoaciduria caused by mutations of SLC7A7, the gene encoding y+LAT1 light chain of system yL for cationic amino acid transport. The pathogenesis...
5.
Barilli A, Gaiani F, Prandi B, Cirlini M, Ingoglia F, Visigalli R, et al.
J Nutr Biochem . 2017 Dec; 54:11-17. PMID: 29216605
Celiac disease (CD) is an immune-mediated enteropathy triggered by ingested gluten in genetically susceptible individuals and sustained by both adaptive and innate immune responses. Recent studies in murine macrophages demonstrated...
6.
Ingoglia F, Visigalli R, Rotoli B, Barilli A, Riccardi B, Puccini P, et al.
J Leukoc Biol . 2016 Oct; 101(3):665-674. PMID: 27733576
l-Carnitine, in addition to playing a fundamental role in the β-oxidation of fatty acids, has been recently identified as a modulator of immune function, although the mechanisms that underlie this...
7.
Ingoglia F, Visigalli R, Rotoli B, Barilli A, Riccardi B, Puccini P, et al.
Biochim Biophys Acta . 2015 Nov; 1858(2):210-9. PMID: 26607009
Carnitine plays a physiologically important role in the β-oxidation of fatty acids, facilitating the transport of long-chain fatty acids across the inner mitochondrial membrane. Distribution of carnitine within the body...
8.
Barilli A, Rotoli B, Visigalli R, Ingoglia F, Cirlini M, Prandi B, et al.
Biochim Biophys Acta . 2015 Jun; 1852(9):1779-86. PMID: 26047680
Celiac disease (CD) is an immune-mediated enteropathy sustained by dietary gluten in susceptible individuals, and characterized by a complex interplay between adaptive and innate responses against gluten peptides (PTG). In...
9.
Ingoglia F, Visigalli R, Rotoli B, Barilli A, Riccardi B, Puccini P, et al.
Biochim Biophys Acta . 2015 Apr; 1848(7):1563-72. PMID: 25883089
Organic cation transporters (OCT1-3) mediate the transport of organic cations including inhaled drugs across the cell membrane, although their role in lung epithelium hasn't been well understood yet. We address...
10.
Barilli A, Atzeri C, Bassanetti I, Ingoglia F, DallAsta V, Bussolati O, et al.
Mol Pharm . 2014 Mar; 11(4):1151-63. PMID: 24592930
Here, we report the antiproliferative/cytotoxic properties of 8-hydroxyquinoline (8-HQ) derivatives on HeLa cells in the presence of transition metal ions (Cu(2+), Fe(3+), Co(2+), Ni(2+)). Two series of ligands were tested,...