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Fernando Lucas-Ruiz

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Articles 21
Citations 214
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Recent Articles
1.
Rodriguez-Ramirez K, Galindo-Romero C, Lucas-Ruiz F, Vidal-Sanz M, Agudo-Barriuso M
Acta Ophthalmol . 2025 Feb; PMID: 39916676
Purpose: To compare the course of retinal ganglion cell (RGC) loss following optic nerve crush (ONC) in male and female mice and to assess the neuroprotective potential of intravitreally administered...
2.
Vidal-Correoso D, Mateo S, Munoz-Morales A, Lucas-Ruiz F, Jover-Aguilar M, Alconchel F, et al.
Transplantation . 2024 Apr; 108(10):e301-e312. PMID: 38578699
Background: Liver transplantation (LT) is crucial for end-stage liver disease patients, but organ shortages persist. Donation after circulatory death (DCD) aims to broaden the donor pool but presents challenges. Complications...
3.
Rodriguez-Ramirez K, Norte-Munoz M, Lucas-Ruiz F, Gallego-Ortega A, Calzaferri F, Garcia-Bernal D, et al.
Front Immunol . 2024 Feb; 15:1340013. PMID: 38384465
Background: Neurological dysfunction and glial activation are common in severe infections such as sepsis. There is a sexual dimorphism in the response to systemic inflammation in both patients and animal...
4.
Cabrera-Maqueda J, Boia R, Lucas-Ruiz F, Gonzalez-Riquelme M, Ambrosio A, Santiago A, et al.
Exp Eye Res . 2023 Aug; 235:109627. PMID: 37619829
The main purpose of this study is to analyze the effects of unilateral optic nerve crush in the gene expression of pro- and anti-inflammatory mediators, and gliosis markers in injured...
5.
Gonzalez-Riquelme M, Lucas-Ruiz F, Galindo-Romero C, Boia R, Ambrosio A, Vidal-Sanz M, et al.
Int J Mol Sci . 2023 Feb; 24(4). PMID: 36834893
Retinal organotypic cultures (ROCs) are used as an in vivo surrogate to study retinal ganglion cell (RGC) loss and neuroprotection. In vivo, the gold standard to study RGC degeneration and...
6.
Nadal-Nicolas F, Galindo-Romero C, Lucas-Ruiz F, Marsh-Amstrong N, Li W, Vidal-Sanz M, et al.
Zool Res . 2023 Jan; 44(1):226-248. PMID: 36594396
Univocal identification of retinal ganglion cells (RGCs) is an essential prerequisite for studying their degeneration and neuroprotection. Before the advent of phenotypic markers, RGCs were normally identified using retrograde tracing...
7.
Lucas-Ruiz F, Mateo S, Jover-Aguilar M, Alconchel F, Martinez-Alarcon L, Torre-Minguela C, et al.
EBioMedicine . 2022 Dec; 87:104419. PMID: 36543018
Background: Innate immunity plays a fundamental role in solid organ transplantation. Myeloid cells can sense danger signals or DAMPs released after tissue or cell damage, such as during ischemia processes....
8.
Lucas-Ruiz F, Penin-Franch A, Pons J, Ramirez P, Pelegrin P, Cuevas S, et al.
Int J Mol Sci . 2022 Nov; 23(22). PMID: 36430874
The nucleotide-binding domain leucine-rich repeat-receptor, pyrin domain-containing-3 (NLRP3) inflammasome contributes to the inflammatory response by activating caspase-1, which in turn participates in the maturation of interleukin (IL)-1β and IL-18, which...
9.
Galindo-Romero C, Norte-Munoz M, Gallego-Ortega A, Rodriguez-Ramirez K, Lucas-Ruiz F, Gonzalez-Riquelme M, et al.
Front Neuroanat . 2022 Oct; 16:994890. PMID: 36213609
Albino and pigmented rat strains are widely used in models to study retinal degeneration and to test new therapies. Here, we have summarized the main topographical and functional characteristics of...
10.
Baroja-Mazo A, Penin-Franch A, Lucas-Ruiz F, Torre-Minguela C, Alarcon-Vila C, Hernandez-Caselles T, et al.
Br J Pharmacol . 2022 Sep; 180(1):111-128. PMID: 36098250
Background And Purpose: A high number of intratumoural infiltrating natural killer (NK) cells is associated with better survival in several types of cancer, constituting an important first line of defence...