Fernando Cabral
Overview
Explore the profile of Fernando Cabral including associated specialties, affiliations and a list of published articles.
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42
Citations
868
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Recent Articles
1.
Coelho M, Mahar R, Belew G, Torres A, Barosa C, Cabral F, et al.
NMR Biomed
. 2022 Sep;
36(2):e4837.
PMID: 36151589
Deuterated water ( H O) is a widely used tracer of carbohydrate biosynthesis in both preclinical and clinical settings, but the significant kinetic isotope effects (KIE) of H can distort...
2.
Barosa C, Shanmugam H, Cabral F, Jones J
Anal Biochem
. 2019 Nov;
590:113511.
PMID: 31759975
p-Aminobenzoic acid (PABA) was evaluated for noninvasive sampling of UDP-glucose in the liver. Six healthy subjects ingested 550 mg PABA during a breakfast meal. Urine was collected 0-2 and 2-4 ...
3.
Ganguly A, Cabral F, Yang H, Patel K
Oncoscience
. 2015 Aug;
2(6):585-95.
PMID: 26244166
Peloruside A is a novel antimitotic drug originally isolated from the marine sponge Mycale hentschieli. Previous studies showed that peloruside A stabilizes microtubules by binding to a site on tubulin...
4.
Kanakkanthara A, Eras J, Northcote P, Cabral F, Miller J
Curr Cancer Drug Targets
. 2013 Nov;
14(1):79-90.
PMID: 24245693
Cancer cell lines selected for resistance to microtubule targeting agents (MTA) often have acquired mutations in the β-tubulin binding sites for these agents. Despite strong correlational evidence, the functional and...
5.
Yin S, Zeng C, Hari M, Cabral F
Cytoskeleton (Hoboken)
. 2013 Oct;
70(12):849-62.
PMID: 24155014
Many mammalian β-tubulin mutations that confer paclitaxel resistance have been characterized, but little is currently known about the role of α-tubulin mutations in drug resistance. Previous studies using two-dimensional gel...
6.
Ganguly A, Yang H, Zhang H, Cabral F, Patel K
Mol Cancer Ther
. 2013 Oct;
12(12):2837-46.
PMID: 24107446
Drugs that target microtubules are potent inhibitors of angiogenesis, but their mechanism of action is not well understood. To explore this, we treated human umbilical vein endothelial cells with paclitaxel,...
7.
Ganguly A, Yang H, Cabral F
Methods Cell Biol
. 2013 Aug;
115:49-62.
PMID: 23973065
Microtubule detachment from microtubule organizing centers is an important cellular process required for normal cell proliferation. When cells enter mitosis, microtubule turnover increases along with a concurrent increase in microtubule...
8.
Ganguly A, Yang H, Sharma R, Patel K, Cabral F
J Biol Chem
. 2012 Nov;
287(52):43359-69.
PMID: 23135278
Although microtubules have long been implicated in cell locomotion, the mechanism of their involvement remains controversial. Most studies have concluded that microtubules play a positive role by regulating actin polymerization,...
9.
Yin S, Zeng C, Hari M, Cabral F
Pharm Res
. 2012 Jun;
29(11):2994-3006.
PMID: 22669706
Purpose: Previous research showed that mutations in β1-tubulin are frequently involved in paclitaxel resistance but the question of whether the mutations are restricted by cell-type specific differences remains obscure. Methods:...
10.
Ganguly A, Bhattacharya R, Cabral F
Cytoskeleton (Hoboken)
. 2012 Mar;
69(5):303-11.
PMID: 22422706
Mitotic centromere associated kinesin (MCAK) is a kinesin related protein with the ability to stimulate microtubule depolymerization. It is found at spindle poles, where it may be involved in poleward...