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Fergus W Hamilton

Explore the profile of Fergus W Hamilton including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 620
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Recent Articles
1.
Arnold D, Read L, Waddington O, Hamilton F, Patole S, Hughes J, et al.
Thorax . 2024 Jul; 79(9):883-885. PMID: 38964858
Pleural infection is usually treated with empirical broad-spectrum antibiotics, but limited data exist on their penetrance into the infected pleural space. We performed a pharmacokinetic study analysing the concentration of...
2.
Hamilton F, Hughes D, Spiller W, Tilling K, Davey Smith G
Eur J Epidemiol . 2024 May; 39(5):451-465. PMID: 38789826
Mendelian randomisation (MR) is an established technique in epidemiological investigation, using the principle of random allocation of genetic variants at conception to estimate the causal linear effect of an exposure...
3.
Wade K, Timpson N, Hamilton F, Sattar N, Carslake D, Davey Smith G
Obesity (Silver Spring) . 2024 May; 32(8):1419-1420. PMID: 38773930
No abstract available.
4.
Wade K, Hamilton F, Carslake D, Sattar N, Davey Smith G, Timpson N
Obesity (Silver Spring) . 2023 Oct; 31(12):2887-2890. PMID: 37845826
Mendelian randomization (MR) is a widely used method that exploits the unique properties of germline genetic variation to strengthen causal inference in relationships between exposures and outcomes. Nonlinear MR allows...
5.
Richmond R, Hamilton F, Davey Smith G
J Clin Endocrinol Metab . 2023 Oct; 109(3):e1316-e1317. PMID: 37823442
No abstract available.
6.
Hamilton F, Abeysekera K, Hamilton W, Timpson N
BMJ Med . 2023 Jul; 2(1):e000467. PMID: 37456363
Objectives: To compare associations between the Gilbert syndrome genotype in European populations, measured bilirubin concentrations, genetically predicted bilirubin using this genotype, and a wide range of health outcomes in a...
7.
Edwards F, Hamilton F
BMJ Med . 2023 Mar; 2(1):e000470. PMID: 36936263
No abstract available.
8.
Hamilton F, Thomas M, Arnold D, Palmer T, Moran E, Mentzer A, et al.
PLoS Med . 2023 Jan; 20(1):e1004174. PMID: 36716318
Background: Sepsis is characterised by dysregulated, life-threatening immune responses, which are thought to be driven by cytokines such as interleukin 6 (IL-6). Genetic variants in IL6R known to down-regulate IL-6...
9.
Hamilton F, Somers J, Mitchell R, Ghazal P, Timpson N
PLoS One . 2022 May; 17(5):e0267399. PMID: 35551540
Introduction: Heme-oxygenase 1 (HMOX1) is a critical stress response gene that catalyzes the multistep oxidation of heme. A GT(n) repeat of variable length in the promoter in has been associated...
10.
Mankelow T, Blair A, Arnold D, Hamilton F, Gillespie K, Anstee D, et al.
Transfus Med . 2022 Mar; 32(3):261-262. PMID: 35332587
No abstract available.